Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CTH | P32929 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.32 |
| ▸ | GGT1 | P19440 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1407278 | 0.79 | — | — | |
| SCHEMBL28738431 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL2310467 | 0.77 | KDM4E (0.41) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| Malonic Acid SCHEMBL9278941 | 0.73 | LDHA (0.43) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL1717828 | 0.73 | HMGCR (0.41) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL41886 | 0.73 | — | — | |
| SCHEMBL12003332 | 0.71 | HMGCR (0.42) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| Hydrochloric Acid SCHEMBL1092821 | 0.70 | HMGCR (0.39) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| Hydrochloric Acid SCHEMBL28883817 | 0.70 | HMGCR (0.39) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| SCHEMBL242144 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070172925-A1 | Ribonucleic acid compound and method of liquid-phase synthesis of oligonucleic acid compound | NIPPON SHINYAKU CO., LTD. (JP) | 2007-07-26 | — | — | US | disclosed |
| EP-1710249-A1 | RIBONUCLEIC ACID COMPOUND AND METHOD OF LIQUID-PHASE SYNTHESIS OF OLIGONUCLEIC ACID COMPOUND | Nippon Shinyaku Co., Ltd. (JP) | 2006-10-11 | — | — | EP | disclosed |
| US-20040058886-A1 | Short interfering RNAs having a hairpin structure containing a non-nucleotide loop | DHARMACON, INC. | 2004-03-25 | — | — | US | disclosed |
| WO-2004015075-A2 | SHORT INTERFERING RNAS HAVING A HAIRPIN STRUCTURE CONTAINING A NON-NUCLEOTIDE LOOP | DHARMACON, INC. (US) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070172925-A1 | Ribonucleic acid compound and method of liquid-phase synthesis of oligonucleic acid compound | RNASEH1, NSUN2, POLR2H | HMGCR 2842/4885CHRM1 4166/4885TBXA2R 3035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.