Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | TEK | Q02763 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374241 | 0.87 | TDP1 (0.59) | RAB9ATDP1ALDH1A1HTTMAPK8 | |
| Hydrochloric Acid SCHEMBL6831889 | 0.85 | RAB9A (0.59) | RAB9ATDP1ALDH1A1ROCK2MAPK8 | |
| SCHEMBL7311036 | 0.84 | TDP1 (0.60) | RAB9ATDP1ALDH1A1HTTROCK2 | |
| SCHEMBL7364681 | 0.83 | RAB9A (0.72) | RAB9ATDP1ALDH1A1ROCK2MAPK10 | |
| SCHEMBL5518685 | 0.83 | RAB9A (0.60) | RAB9ATDP1ALDH1A1ROCK2KDM4E | |
| SCHEMBL5755198 | 0.83 | RAB9A (0.56) | RAB9ATDP1ALDH1A1HTTROCK2 | |
| SCHEMBL5518570 | 0.83 | RAB9A (0.56) | RAB9ATDP1ALDH1A1ROCK2KDM4E | |
| SCHEMBL7312518 | 0.82 | RAB9A (0.59) | RAB9ATDP1ALDH1A1KDM4EDRD1 | |
| SCHEMBL742272 | 0.82 | RAB9A (0.75) | RAB9ATDP1ALDH1A1HTTROCK2 | |
| SCHEMBL5526358 | 0.81 | RAB9A (0.58) | RAB9ATDP1ALDH1A1HTTROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | ARENA PHARMACEUTICALS, INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | MCHR1, GPR119, MCHR2 | RAB9A 902/4885TDP1 1807/4885ALDH1A1 2069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.