Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498067 | 0.98 | ATM (0.58) | ATMALDH1A1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL4812065 | 0.85 | ATM (0.65) | ATMALDH1A1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL7548624 | 0.85 | ATM (0.65) | ATMALDH1A1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL8273595 | 0.84 | ATM (0.63) | ATMALDH1A1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL23096828 | 0.81 | TDP1 (0.45) | ATMALDH1A1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL12443868 | 0.81 | DDB1 (0.44) | ATMALDH1A1SMN1; SMN2TDP1KMT2A | |
| SCHEMBL22623120 | 0.81 | ATM (0.59) | ATMALDH1A1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL5857321 | 0.81 | KMT2A (0.45) | ATMALDH1A1SMN1; SMN2TDP1KMT2A | |
| SCHEMBL4816120 | 0.81 | L3MBTL1 (0.52) | ALDH1A1SMN1; SMN2L3MBTL1NPC1HSD17B10 | |
| SCHEMBL10337221 | 0.78 | ATM (0.56) | ATMALDH1A1SMN1; SMN2L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114191439-B | Application of C-23-position nitrogen-containing heterocyclic derivative of A-cycloisoxazole-ring hederagenin | 烟台大学 | 2023-04-25 | — | — | CN | claimed |
| CN-114213501-B | C-23 nitrogen-containing heterocyclic derivative of cycloisoxazole ring hederagenin and preparation method thereof | 烟台大学 | 2023-01-20 | — | — | CN | claimed |
| CN-114191439-B | Application of C-23-position nitrogen-containing heterocyclic derivative of A-cycloisoxazole-ring hederagenin | 烟台大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-114213501-B | C-23 nitrogen-containing heterocyclic derivative of cycloisoxazole ring hederagenin and preparation method thereof | 烟台大学 | 2023-01-20 | — | — | CN | disclosed |
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1698626-A1 | AMIDOPYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-0831826-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PROTEINASE INHIBITOR AND A MONOGLYCERIDE | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996039142-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PROTEINASE INHIBITOR AND A MONOGLYCERIDE | F. HOFFMANN-LA ROCHE AG (CH) | 1996-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | PTGER1, PTGS1, PTGER2 | ATM 2599/4885ALDH1A1 171/4885SMN1; SMN2 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.