Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14268831 | 0.94 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL5021832 | 0.91 | MEN1 (0.56) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL11753893 | 0.88 | MEN1 (0.54) | MEN1KMT2AARHTTDPP4 | |
| SCHEMBL16213548 | 0.85 | KMT2A (0.62) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL5531703 | 0.84 | JUN (0.52) | NPC1RAB9AHTTLMNASMN1; SMN2 | |
| SCHEMBL16521695 | 0.83 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL12671928 | 0.81 | DPP4 (0.58) | MEN1KMT2AARHTTDPP4 | |
| SCHEMBL17047686 | 0.81 | AR (0.57) | MEN1KMT2AARHTTDPP4 | |
| SCHEMBL14149917 | 0.81 | HTT (0.48) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL13401373 | 0.81 | MEN1 (0.62) | NPC1RAB9AMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403859-B1 | MOLECULAR TWEEZERS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | UNIV CALIFORNIA (US) | 2017-05-03 | — | — | EP | disclosed |
| EP-2403859-B1 | MOLECULAR TWEEZERS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | UNIV CALIFORNIA (US) | 2017-05-03 | — | — | EP | disclosed |
| US-8168327-B2 | Imide derivative, material for organic electroluminescent device and organic electroluminescent device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-20070160905-A1 | NOVEL IMIDE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070160905-A1 | NOVEL IMIDE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-07-12 | — | — | US | disclosed |