SCHEMBL17047686

SCHEMBL17047686

CC1=C(C)C(=O)N(c2cccc(C(F)(F)F)c2)C1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.57
CYP1A2 P05177 1/20 0.56
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
PARP1 P09874 1/20 0.53
PARP15 Q460N3 1/20 0.53
PARP10 Q53GL7 1/20 0.53
DPP4 P27487 1/20 0.51
ALOX5 P09917 1/20 0.49
HTT P42858 1/20 0.49
CYP2C8 P10632 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
NOTUM Q6P988 1/20 0.48
ALDH1A1 P00352 2/20 0.47
TSHR P16473 1/20 0.47
POLB P06746 1/20 0.47
PMM2 O15305 1/20 0.46
MPI P34949 1/20 0.46
PHOSPHO1 Q8TCT1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14150069 0.91 DPP4 (0.50) ARCYP1A2MEN1KMT2APARP1
SCHEMBL14106316 0.87 GRM5 (0.49) ARCYP1A2MEN1KMT2APARP1
SCHEMBL12671928 0.83 DPP4 (0.58) ARCYP1A2MEN1KMT2ADPP4
SCHEMBL11753893 0.83 MEN1 (0.54) ARCYP1A2MEN1KMT2ADPP4
SCHEMBL17047810 0.82 XPO1 (0.56) ARCYP1A2PARP1PARP15PARP10
SCHEMBL5530144 0.81 NPC1 (0.58) ARCYP1A2MEN1KMT2ADPP4
SCHEMBL5021832 0.81 MEN1 (0.56) ARCYP1A2MEN1KMT2ADPP4
SCHEMBL3180022 0.79 MGLL (0.64) ARCYP1A2MEN1KMT2AHTT
SCHEMBL3656289 0.79 CYP1A2 (0.52) ARCYP1A2MEN1KMT2ADPP4
SCHEMBL17047743 0.78 RAD51 (0.45) PARP1PARP15PARP10MPIPHOSPHO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106029652-B Plant growth regulating compound 先正达参股股份有限公司 2019-08-13 CN disclosed
EP-3110808-B1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-08-29 EP disclosed
US-9751867-B2 Plant growth regulating compounds SYNGENTA PARTICIPATIONS AG (CH) 2017-09-05 US disclosed
EP-3110808-A1 PLANT GROWTH REGULATING COMPOUNDS Syngenta Participations AG (CH) 2017-01-04 EP disclosed
US-20160368900-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-12-22 US disclosed
CN-106029652-A Plant growth regulating compounds 先正达参股股份有限公司 2016-10-12 CN disclosed
WO-2015128321-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2015-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160368900-A1 PLANT GROWTH REGULATING COMPOUNDS GHDC, GAK, EIF4G2 AR 4788/4885CYP1A2 2741/4885MEN1 4325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.