Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | SHBG | P04278 | 3/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | THPO | P40225 | 1/20 | 0.67 |
| ▸ | GMNN | O75496 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530501 | 1.00 | HSD17B10 (0.67) | HSD17B10LMNAMEN1MAPTKMT2A | |
| SCHEMBL29635930 | 0.91 | HSD17B10 (0.66) | HSD17B10LMNAMEN1MAPTKMT2A | |
| SCHEMBL4665285 | 0.84 | ESR1 (0.66) | HSD17B10LMNAMEN1MAPTKMT2A | |
| SCHEMBL2596534 | 0.82 | ESR1 (0.77) | HSD17B10LMNAMEN1MAPTKMT2A | |
| SCHEMBL1048371 | 0.82 | ESR1 (0.77) | HSD17B10LMNAMEN1MAPTKMT2A | |
| SCHEMBL13123060 | 0.82 | ESR1 (0.77) | HSD17B10LMNAMEN1MAPTKMT2A | |
| SCHEMBL31544736 | 0.82 | ESR1 (0.77) | HSD17B10LMNAMEN1MAPTKMT2A | |
| SCHEMBL1080502 | 0.81 | HSD17B10 (0.85) | HSD17B10LMNAMEN1MAPTKMT2A | |
| 2-Methoxyestradiol SCHEMBL23261536 | 0.80 | CYP19A1 (1.00) | HSD17B10LMNAMEN1MAPTKMT2A | |
| 2-Methoxyestradiol SCHEMBL7052497 | 0.80 | CYP19A1 (1.00) | HSD17B10LMNAMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275935-A1 | Estratriene Derivatives | CRYPTOPHARMA PTY LTD (AU) | 2007-11-29 | — | — | US | disclosed |
| CN-1867577-A | Estratriene derivatives | CRYPTOPHARMA PTY LTD (AU) | 2006-11-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275935-A1 | Estratriene Derivatives | ESR2, ESRRB, NR3C2 | HSD17B10 219/4885LMNA 3831/4885MEN1 2306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.