SCHEMBL1048371

SCHEMBL1048371

COc1c(O)ccc2c1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@H](O)CC[C@@H]12

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.77
ESR2 Q92731 8/20 0.77
LMNA P02545 6/20 0.77
MEN1 O00255 4/20 0.77
MAPT P10636 4/20 0.77
KMT2A Q03164 4/20 0.77
GAA P10253 3/20 0.77
KDM4E B2RXH2 2/20 0.77
G6PD P11413 2/20 0.77
PKM P14618 2/20 0.77
MAPK1 P28482 2/20 0.77
MPI P34949 1/20 0.77
CYP19A1 P11511 3/20 0.72
STS P08842 2/20 0.67
HSD17B10 Q99714 6/20 0.61
CYP1A2 P05177 3/20 0.60
CYP3A4 P08684 3/20 0.60
CYP1B1 Q16678 3/20 0.60
TSHR P16473 3/20 0.60
CYP1A1 P04798 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2596534 1.00 ESR1 (0.77) ESR1ESR2LMNAMEN1MAPT
SCHEMBL13123060 1.00 ESR1 (0.77) ESR1ESR2LMNAMEN1MAPT
SCHEMBL31544736 1.00 ESR1 (0.77) ESR1ESR2LMNAMEN1MAPT
SCHEMBL6883109 0.89 ESR1 (0.73) ESR1ESR2LMNAMEN1MAPT
SCHEMBL6883111 0.89 ESR1 (0.73) ESR1ESR2LMNAMEN1MAPT
SCHEMBL4665285 0.89 ESR1 (0.66) ESR1ESR2LMNAMEN1MAPT
SCHEMBL224399 0.87 ESR1 (1.00) ESR1ESR2LMNAMEN1MAPT
SCHEMBL6009933 0.87 ESR1 (1.00) ESR1ESR2LMNAMEN1MAPT
SCHEMBL13123059 0.87 ESR1 (1.00) ESR1ESR2LMNAMEN1MAPT
SCHEMBL224398 0.87 ESR1 (1.00) ESR1ESR2LMNAMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 409 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119894916-A Method for purifying 2-methoxyestradiol from 4-methoxyestradiol and intermediates thereof 工业化学有限公司 2025-04-25 CN claimed
WO-2023242712-A1 PROCESS FOR THE PURIFICATION OF 2-METHOXYESTRADIOL FROM 4- METHOXYESTRADIOL AND INTERMEDIATES OF THE PROCESS INDUSTRIALE CHIMICA S.R.L. (IT) 2023-12-21 WO claimed
CN-115453023-A Serum diagnosis marker of non-hyperandrogenic polycystic ovary syndrome and screening method and application thereof 南京鼓楼医院 2022-12-09 CN claimed
EP-2991621-B1 TWO-LAYER OCULAR IMPLANT RETINA FOUND OF THE SOUTHWEST (US) 2020-12-09 EP claimed
CN-110596254-A Kit for detecting estrogen and/or active metabolite thereof and application thereof 徐州医科大学 2019-12-20 CN claimed
US-10449145-B2 Two-layer ocular implant RETINA FOUNDATION OF THE SOUTHWEST (US) 2019-10-22 US claimed
US-20180353427-A1 TWO-LAYER OCULAR IMPLANT RETINA FOUNDATION OF THE SOUTHWEST 2018-12-13 US claimed
US-20160081920-A1 TWO-LAYER OCULAR IMPLANT RETINA FOUNDATION OF THE SOUTHWEST 2016-03-24 US claimed
EP-2991621-A2 TWO-LAYER OCULAR IMPLANT Odin Biotech (US) 2016-03-09 EP claimed
WO-2014179568-A2 TWO-LAYER OCULAR IMPLANT ODIN BIOTECH (US) 2014-11-06 WO claimed
US-6200966-B1 FOR TREATING CHRONIC AND ACUTE INFLAMMATION OF AIRWAYS, INCLUDING ASTHMATIC CONDITIONS AMRAD OPERATIONS PTY. LTD. (AU) 2001-03-13 US claimed
WO-2001014405-A2 METHODS OF OBTAINING 2-METHOXYESTRADIOL OF HIGH PURITY ENTREMED, INC. (US) 2001-03-01 WO claimed
JP-2000507923-A 2000-06-27 JP claimed
EP-0923376-A1 TREATMENT OF ASTHMA AND AIRWAY DISEASES Amrad Operations Pty.,Ltd. (AU) 1999-06-23 EP claimed
CN-1218401-A Treatment of asthma and airway diseases AMRAD OPERATIONS PTY LTD (AU) 1999-06-02 CN claimed
WO-1999001142-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING AN ANGIOSTATIC STEROID COMBINED WITH A HYALURONAN HYAL PHARMACEUTICAL CORPORATION (CA) 1999-01-14 WO claimed
EP-0866969-A1 METHOD OF CANCER DETECTION IMMUNA CARE CORPORATION (US) 1998-09-30 EP claimed
WO-1997042958-A1 TREATMENT OF ASTHMA AND AIRWAY DISEASES AMRAD OPERATIONS PTY. LTD. (AU) 1997-11-20 WO claimed
WO-1997011374-A1 METHOD OF CANCER DETECTION IMMUNA CARE CORPORATION (US) 1997-03-27 WO claimed
US-5521168-A TREATING GLAUCOMA ALCON LABORATORIES, INC. (US) 1996-05-28 US claimed