⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10612775 | 0.73 | — | — | |
| SCHEMBL11556838 | 0.71 | — | — | |
| SCHEMBL3834024 | 0.71 | — | — | |
| SCHEMBL1033676 | 0.71 | — | — | |
| SCHEMBL9680270 | 0.71 | — | — | |
| SCHEMBL10688324 | 0.71 | — | — | |
| SCHEMBL4969205 | 0.69 | — | — | |
| SCHEMBL59407 | 0.69 | ALDH1A1 (0.44) | — | |
| SCHEMBL191971 | 0.69 | — | — | |
| SCHEMBL11508400 | 0.69 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113242-B1 | CEPHALOSPORIN DERIVATIVES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-11-08 | — | — | EP | claimed |
| JP-56081592-A | — | — | None | — | — | JP | disclosed |
| EP-3475276-B1 | THIAZOLE DERIVATIVES USEFUL AS MUTANT IDH1 INHIBITORS FOR TREATING CANCER | US HEALTH (US) | 2021-03-31 | — | — | EP | disclosed |
| US-20070027190-A1 | Antibacterial fab i inhibitors | OSCIENT PHARMACEUTICALS CORPORATION | 2007-02-01 | — | — | US | disclosed |
| WO-2004064837-A1 | ANTIBACTERIAL FAB I INHIBITORS | OSCIENT PHARMACEUTICALS (US) | 2004-08-05 | — | — | WO | disclosed |
| CN-1040429-C | improved process for the preparation of thioacetamide | ROHM & HAAS (US) | 1998-10-28 | — | — | CN | disclosed |
| CN-1102182-A | Improved process for the preparation of thioacetamide | MONSANTO CO (US) | 1995-05-03 | — | — | CN | disclosed |
| US-5395931-A | 6-amido-1-methyl-2-(substituted-thio)carbapenems | MERCK & CO., INC. (US) | 1995-03-07 | — | — | US | disclosed |
| EP-0222022-B1 | PROCESS FOR PRODUCING BETA-LACTAM DERIVATIVES | Otsuka Kagaku Kabushiki Kaisha (JP) | 1992-09-23 | — | — | EP | disclosed |
| US-5138050-A | 6-amido-1-methyl carbapenems | MERCK & CO., INC. (US) | 1992-08-11 | — | — | US | disclosed |
| US-4068073-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4067880-A | SULFOALKYL-OXADIAZOLE THIOLS | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4066761-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
| US-4064242-A | ANTIBACTERIAL AGENTS | SMITHKLINE CORPORATION (US) | 1977-12-20 | — | — | US | disclosed |
| US-4059591-A | Ureidoalkyl substituted tetrazole thiol intermediates for preparing cephalosporins | SMITHKLINE CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |
| US-4057631-A | CEPHALOSPORINS, BACTERICIDE | SMITHKLINE CORPORATION (US) | 1977-11-08 | — | — | US | disclosed |
| US-4048311-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4041162-A | ANTIBIOTICS, BACTERICIDES | SMITHKLINE CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
| US-4034092-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |
| US-4025626-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |