⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208010 | 0.82 | TSHR (0.39) | — | |
| SCHEMBL9843584 | 0.82 | — | — | |
| SCHEMBL3073414 | 0.82 | — | — | |
| SCHEMBL10456046 | 0.82 | — | — | |
| SCHEMBL2494440 | 0.79 | — | — | |
| SCHEMBL2205880 | 0.79 | — | — | |
| SCHEMBL2396665 | 0.79 | — | — | |
| SCHEMBL11854035 | 0.79 | TSHR (0.36) | — | |
| SCHEMBL12019019 | 0.79 | TSHR (0.36) | — | |
| SCHEMBL707858 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220249687-A1 | BIS(2-HALOACETAMIDO)-COMPOUNDS FOR USE AS LINKING AGENTS AND RESULTANT PRODUCTS WHICH COMPRISE ANTIBODIES, HALF-ANTIBODIES AND ANTIBODY FRAGMENTS | THE UNIVERSITY OF BATH (GB) | 2022-08-11 | — | — | US | disclosed |
| EP-3990023-A1 | BIS(2-HALOACETAMIDO)-COMPOUNDS FOR USE AS LINKING AGENTS AND RESULTANT PRODUCTS WHICH COMPRISE ANTIBODIES, HALF-ANTIBODIES AND ANTIBODY FRAGMENTS | The University Of Bath (GB) | 2022-05-04 | — | — | EP | disclosed |
| WO-2020260514-A1 | BIS(2-HALOACETAMIDO)-COMPOUNDS FOR USE AS LINKING AGENTS AND RESULTANT PRODUCTS WHICH COMPRISE ANTIBODIES, HALF-ANTIBODIES AND ANTIBODY FRAGMENTS | THE UNIVERSITY OF BATH (GB) | 2020-12-30 | — | — | WO | disclosed |
| CN-101248130-B | Flame-retardant flexible polyurethane foam | SUPRESTA LLC | 2011-11-09 | — | — | CN | disclosed |
| WO-2008130381-A2 | POLYGLUTAMIC ACID COMPOSITIONS AND THEIR USE AS IMMUNOGENS | WYETH (US) | 2008-10-30 | — | — | WO | disclosed |
| CN-101248130-A | Flame-retardant flexible polyurethane foam | SUPRESTA LLC (US) | 2008-08-20 | — | — | CN | disclosed |
| US-20060078921-A1 | Biomarkers and expression profiles for toxicology | BOESS FRANZISKA | 2006-04-13 | — | — | US | disclosed |
| EP-0192601-B1 | FLAME-RETARDANT FOR POLYURETHANES | CIBA-GEIGY AG (CH) | 1990-10-31 | — | — | EP | disclosed |
| EP-0254683-A2 | Flame-retardant compositions | CIBA-GEIGY AG (CH) | 1988-01-27 | — | — | EP | disclosed |
| EP-0192601-A2 | Flame-retardant for polyurethanes | CIBA-GEIGY AG (CH) | 1986-08-27 | — | — | EP | disclosed |
| US-3976769-A | INSECTICIDE | AIRWICK INDUSTRIES, INC. (US) | 1976-08-24 | — | — | US | disclosed |