Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 6/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | MAP3K11 | Q16584 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.38 |
| ▸ | CDK9 | P50750 | 3/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531542 | 0.84 | IMPDH2 (0.44) | IMPDH2IMPDH1PRKCQPRKCDLYN | |
| SCHEMBL5533120 | 0.76 | KDM1A (0.40) | LRRK2DYRK1A | |
| Hydrochloric Acid SCHEMBL4952344 | 0.70 | PRKCQ (0.59) | IMPDH2IMPDH1PRKCQPRKCDLYN | |
| SCHEMBL5485659 | 0.68 | IMPDH2 (0.73) | IMPDH2IMPDH1RIPK1GABRPGABRD | |
| SCHEMBL5527077 | 0.67 | PRKCQ (0.51) | IMPDH2IMPDH1PRKCQPRKCDLYN | |
| SCHEMBL5533125 | 0.67 | PRKCQ (0.43) | IMPDH2IMPDH1PRKCQPRKCDLYN | |
| SCHEMBL4951383 | 0.67 | PRKCQ (0.69) | PRKCQPRKCDLYN | |
| SCHEMBL1146649 | 0.67 | BRD4 (0.50) | IMPDH2IMPDH1PRKCQRIPK1MAP3K11 | |
| SCHEMBL1146448 | 0.66 | PRKCQ (0.60) | IMPDH2IMPDH1PRKCQPRKCDMAP3K11 | |
| SCHEMBL2645009 | 0.65 | MAP3K11 (0.56) | MAP3K11CYP3A4CYP2D6LRRK2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070082880-A1 | Thieno [2,3-B] pyridine-5-carbonitriles as protein kinase inhibitors | WYETH | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082880-A1 | Thieno [2,3-B] pyridine-5-carbonitriles as protein kinase inhibitors | MAP4K2, CNKSR1, MAP3K1 | IMPDH2 2088/4885IMPDH1 1537/4885PRKCQ 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.