Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039718 | 0.92 | MEN1 (0.35) | MEN1KMT2APDE5AL3MBTL1KCNA5 | |
| SCHEMBL4036499 | 0.92 | MEN1 (0.34) | MEN1KMT2APDE5AL3MBTL1KCNA5 | |
| SCHEMBL14511038 | 0.92 | L3MBTL1 (0.36) | MEN1KMT2AL3MBTL1KCNA5RIPK1 | |
| SCHEMBL4041319 | 0.91 | L3MBTL1 (0.35) | MEN1KMT2APDE5AL3MBTL1KCNA5 | |
| SCHEMBL4036817 | 0.91 | MEN1 (0.34) | MEN1KMT2APDE5AL3MBTL1KCNA5 | |
| SCHEMBL13930036 | 0.91 | PDE5A (0.35) | MEN1KMT2APDE5AL3MBTL1KCNA5 | |
| SCHEMBL4036395 | 0.90 | DRD2 (0.39) | MEN1KMT2AL3MBTL1KCNA5LMNA | |
| SCHEMBL4036175 | 0.90 | MAPT (0.35) | MEN1KMT2APDE5AL3MBTL1KCNA5 | |
| SCHEMBL13917243 | 0.90 | MEN1 (0.33) | MEN1KMT2APDE5AL3MBTL1KCNA5 | |
| SCHEMBL13948817 | 0.90 | PLA2G1B (0.34) | MEN1KMT2APDE5AL3MBTL1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064316-A1 | BICYCLIC HETEROCYCLES AS HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-07 | — | — | WO | disclosed |