Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | EYA2 | O00167 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10002665 | 0.84 | TDP1 (0.43) | LMNATDP1EYA2APPACE | |
| SCHEMBL28206109 | 0.81 | CA12 (0.43) | LMNAALDH1A1FFAR3TDP1EYA2 | |
| SCHEMBL938369 | 0.81 | GRIN2D (0.39) | LMNAALDH1A1FFAR3ALDH2TDP1 | |
| SCHEMBL10654749 | 0.81 | ALDH1A1 (0.42) | LMNAALDH1A1FFAR3ALDH2TDP1 | |
| SCHEMBL24375 | 0.81 | — | — | |
| SCHEMBL104168 | 0.81 | — | — | |
| SCHEMBL8891629 | 0.79 | LMNA (0.40) | LMNAALDH1A1FFAR3ALDH2TDP1 | |
| SCHEMBL2825457 | 0.79 | — | — | |
| SCHEMBL3885815 | 0.78 | — | — | |
| SCHEMBL3887107 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-1434878-A4 | NUCLEIC ACID CONSTRUCTS CAPABLE OF HIGH EFFICIENCY DELIVERY OF POLYNUCLEOTIDES INTO DNA CONTAINING ORGANELLES AND METHODS OF UTILIZING SAME | YEDA RES & DEV (IL) | 2007-03-14 | — | — | EP | disclosed |
| EP-1434878-A2 | NUCLEIC ACID CONSTRUCTS CAPABLE OF HIGH EFFICIENCY DELIVERY OF POLYNUCLEOTIDES INTO DNA CONTAINING ORGANELLES AND METHODS OF UTILIZING SAME | YEDA RESEARCH AND DEVELOPMENT Co. LTD. (IL) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003025195-A2 | NUCLEIC ACID CONSTRUCTS FOR THE DELIVERY OF POLYNUCLEOTIDES INTO DNA-CONTAINING ORGANELLES,AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2003-03-27 | — | — | WO | disclosed |