Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709158 | 0.84 | ADRB2 (0.46) | ADRB2ADRB1DRD3DRD2ABCB11 | |
| SCHEMBL1800394 | 0.81 | ADRB2 (0.70) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL3834974 | 0.81 | ADRB2 (0.82) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| Hydrochloric Acid SCHEMBL6181224 | 0.80 | ADRB2 (0.62) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL1799411 | 0.79 | ADRB2 (0.60) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL1804802 | 0.79 | ADRB2 (0.67) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL1803827 | 0.78 | ADRB2 (0.81) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL1797660 | 0.78 | ADRB2 (0.51) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL1801359 | 0.78 | ADRB2 (0.71) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL1801926 | 0.77 | ADRB2 (0.55) | ADRB2ADRB1DRD3DRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007538036-A | — | — | 2007-12-27 | — | — | JP | claimed |
| EP-1755590-A1 | COMBINATIONS OF GLYCOPYRROLATE AND BETA2 ADRENOCEPTOR AGONISTS | Novartis AG (CH) | 2007-02-28 | — | — | EP | claimed |
| EP-1715860-A1 | COMBINATION OF BENZOTHIAZOL-2-ONE BETA2 ADRENOCEPTOR AGONISTS AND CORTICOSTEROIDS FOR THE TREATMENT OF RESPIRATORY DISEASES | Novartis AG (CH) | 2006-11-02 | — | — | EP | claimed |
| WO-2005110402-A1 | COMBINATIONS OF GLYCOPYRROLATE AND BETA2 ADRENOCEPTOR AGONISTS | NOVARTIS AG (CH) | 2005-11-24 | — | — | WO | claimed |
| WO-2005074924-A1 | COMBINATION OF BENZOTHIAZOL-2-ONE BETA2 ADRENOCEPTOR AGONISTS AND CORTICOSTEROIDS FOR THE TREATMENT OF RESPIRATORY DISEASES | NOVARTIS AG (CH) | 2005-08-18 | — | — | WO | claimed |
| EP-1755590-A1 | COMBINATIONS OF GLYCOPYRROLATE AND BETA2 ADRENOCEPTOR AGONISTS | Novartis AG (CH) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005110402-A1 | COMBINATIONS OF GLYCOPYRROLATE AND BETA2 ADRENOCEPTOR AGONISTS | NOVARTIS AG (CH) | 2005-11-24 | — | — | WO | disclosed |