Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 1.00 |
| ▸ | HTR7 | P34969 | 8/20 | 0.75 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.75 |
| ▸ | HTR2A | P28223 | 4/20 | 0.73 |
| ▸ | HTR2C | P28335 | 1/20 | 0.73 |
| ▸ | DRD2 | P14416 | 3/20 | 0.70 |
| ▸ | CTSK | P43235 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenharmane SCHEMBL9696484 | 0.99 | GRIN2B (0.97) | GRIN2BHTR7CHRM4HTR2AHTR2C | |
| SCHEMBL18087743 | 0.86 | GRIN2B (0.76) | GRIN2BHTR7CHRM4HTR2AHTR2C | |
| SCHEMBL8402972 | 0.84 | HTR2A (1.00) | GRIN2BHTR7CHRM4HTR2AHTR2C | |
| SCHEMBL8402971 | 0.84 | HTR2A (0.74) | GRIN2BHTR7CHRM4HTR2AHTR2C | |
| SCHEMBL10924004 | 0.82 | GRIN2B (0.70) | GRIN2BHTR7CHRM4HTR2AHTR2C | |
| SCHEMBL5532807 | 0.82 | GRIN2B (0.70) | GRIN2BHTR7CHRM4HTR2AHTR2C | |
| SCHEMBL21883968 | 0.82 | GRIN2B (0.70) | GRIN2BHTR7CHRM4HTR2AHTR2C | |
| SCHEMBL29756361 | 0.82 | GRIN2B (0.70) | GRIN2BHTR7CHRM4HTR2AHTR2C | |
| SCHEMBL8322968 | 0.82 | GRIN2B (0.70) | GRIN2BHTR7CHRM4HTR2AHTR2C | |
| SCHEMBL6651828 | 0.81 | HTR7 (0.69) | GRIN2BHTR7CHRM4HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017053886-A2 | METHOD OF SCREENING FOR AGENTS FOR DIFFERENTIATING STEM CELLS | MINERVA BIOTECHNOLOGIES CORPORATION (US) | 2017-03-30 | — | — | WO | disclosed |
| US-5169852-A | Anorexigenic agents | NEUREX CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |