Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956487 | 0.92 | L3MBTL1 (0.46) | SMN1; SMN2L3MBTL1MAPTNPSR1HPGD | |
| SCHEMBL16950723 | 0.86 | L3MBTL1 (0.45) | L3MBTL1MAPTNPSR1KMT2AMEN1 | |
| SCHEMBL7669246 | 0.85 | ALDH1A1 (0.46) | SMN1; SMN2L3MBTL1MAPTNPSR1HPGD | |
| SCHEMBL3085229 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2L3MBTL1MAPTHPGDCYP1A2 | |
| SCHEMBL1053518 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL1MAPTNPSR1MAPK1 | |
| SCHEMBL16953073 | 0.82 | KMT2A (0.51) | SMN1; SMN2L3MBTL1HPGDKMT2ATSHR | |
| SCHEMBL2806322 | 0.80 | L3MBTL1 (0.50) | SMN1; SMN2L3MBTL1MAPTNPSR1HPGD | |
| SCHEMBL1057947 | 0.80 | ALDH1A1 (0.43) | SMN1; SMN2L3MBTL1MAPTNPSR1HPGD | |
| SCHEMBL2353503 | 0.79 | ALDH1A1 (0.47) | SMN1; SMN2L3MBTL1MAPTNPSR1ATM | |
| SCHEMBL16957328 | 0.78 | CYP4F2 (0.42) | L3MBTL1MAPTNPSR1ATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007123718-A1 | 1-HETEROCYCLYLAMINO-2-HYDROXY-3-AMINO-ω-ARYLALKANES | VITAE PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | WO | disclosed |