Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,4-Diethoxybenzene SCHEMBL11794798 | 0.78 | NQO1 (0.93) | NQO1ADRA2AALDH1A1TSHRTDP1 | |
| SCHEMBL5529092 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KMT2ATSHRSMN1; SMN2CA12 | |
| SCHEMBL5532994 | 0.77 | NQO1 (0.64) | NQO1ADRA2AALDH1A1KMT2ACYP1A2 | |
| 1,4-Diethoxybenzene SCHEMBL28074334 | 0.76 | NQO1 (0.70) | NQO1ALDH1A1KMT2ACYP1A2TSHR | |
| SCHEMBL8762877 | 0.76 | NQO1 (0.70) | NQO1ADRA2AALDH1A1KMT2ACYP1A2 | |
| SCHEMBL8762872 | 0.76 | NQO1 (0.70) | NQO1ADRA2AALDH1A1KMT2ACYP1A2 | |
| SCHEMBL4401293 | 0.76 | NQO1 (0.70) | NQO1ADRA2AALDH1A1KMT2ACYP1A2 | |
| SCHEMBL230798 | 0.76 | NQO1 (0.56) | NQO1ADRA2AALDH1A1KMT2ACYP1A2 | |
| 1,4-Diethoxybenzene SCHEMBL124015 | 0.75 | NQO1 (1.00) | NQO1ADRA2AALDH1A1TSHRTDP1 | |
| 1,4-Diethoxybenzene SCHEMBL28186701 | 0.75 | NQO1 (1.00) | NQO1ADRA2AALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241770-B2 | Hydronopol derivatives as agonists on human ORL1 receptors | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-07-10 | — | — | US | disclosed |
| US-20050131004-A1 | Hydronopol derivatives as agonists on human ORL1 receptors | SOLVAY PHARMACEUTICALS GMBH. | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131004-A1 | Hydronopol derivatives as agonists on human ORL1 receptors | OPRL1, ORMDL3, OGFRL1 | NQO1 1865/4885ADRA2A 223/4885ALDH1A1 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.