Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ESRRB | O95718 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068628 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPK1LMNARAB9AMAPT | |
| SCHEMBL11408016 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPK1LMNARAB9AMAPT | |
| SCHEMBL548361 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPK1LMNARAB9AMAPT | |
| SCHEMBL18012242 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPK1LMNARAB9AMAPT | |
| SCHEMBL11215327 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPK1LMNARAB9AMAPT | |
| SCHEMBL11236021 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPK1LMNARAB9AMAPT | |
| SCHEMBL11425133 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MAPK1LMNARAB9AMAPT | |
| SCHEMBL10061925 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPK1LMNARAB9AMAPT | |
| SCHEMBL11496915 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPK1LMNARAB9AMAPT | |
| SCHEMBL18012243 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPK1LMNARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776351-A1 | UV FILTER | MERCK PATENT GmbH (DE) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006018104-A1 | UV FILTER | MERCK PATENT GMBH (DE) | 2006-02-23 | — | — | WO | disclosed |