SCHEMBL10061925

SCHEMBL10061925

CC(=O)C(C#N)=C(c1ccccc1)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
LMNA P02545 3/20 0.51
MAPK1 P28482 2/20 0.51
MAPT P10636 2/20 0.51
XBP1 P17861 2/20 0.51
NPSR1 Q6W5P4 2/20 0.51
RAB9A P51151 1/20 0.51
CES2 O00748 3/20 0.48
CES1 P23141 3/20 0.48
DHODH Q02127 1/20 0.42
HPGD P15428 1/20 0.40
TSHR P16473 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
ESR1 P03372 1/20 0.38
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYP19A1 P11511 2/20 0.38
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17212284 0.87 CES2 (0.56) ALDH1A1MAPK1MAPTXBP1NPSR1
SCHEMBL13959952 0.84 ALDH1A1 (0.51) ALDH1A1LMNAMAPK1MAPTXBP1
SCHEMBL28420371 0.84 ALDH1A1 (0.51) ALDH1A1LMNAMAPK1MAPTXBP1
Ethane SCHEMBL5679245 0.84 ALDH1A1 (0.51) ALDH1A1LMNAMAPK1MAPTXBP1
Water SCHEMBL11778081 0.83 ALDH1A1 (0.50) ALDH1A1LMNAMAPK1MAPTXBP1
SCHEMBL269364 0.83 ALDH1A1 (0.50) ALDH1A1LMNAMAPK1MAPTXBP1
SCHEMBL10595234 0.82 ALDH1A1 (0.49) ALDH1A1LMNAMAPK1MAPTXBP1
SCHEMBL2139192 0.80 ALDH1A1 (0.47) ALDH1A1LMNAMAPK1MAPTXBP1
SCHEMBL10078738 0.80 ALDH1A1 (0.43) ALDH1A1LMNAMAPK1MAPTXBP1
Ethylene SCHEMBL28481468 0.80 ALDH1A1 (0.47) ALDH1A1LMNAMAPK1MAPTXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-20230167363-A1 LIQUID CRYSTAL COMPOSITION CONTAINING BENZOCHROMENE COMPOUND AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO.,LTD. (CN) 2023-06-01 US disclosed
US-20220185758-A1 Oligomeric Materials for UV Blocking Applications and Methods Thereof AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2022-06-16 US disclosed
US-9238609-B2 Dicarboxylic acid monomers and methods of making and using the same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-01-19 US disclosed
US-20150336869-A1 DICARBOXYLIC ACID MONOMERS AND METHODS OF MAKING AND USING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-26 US disclosed
US-20150322200-A1 AMORPHOUS POLYESTER COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-12 US disclosed
US-20150306002-A1 3-HYDROXY-4-OXO-4H-PYRAN- OR 3-HYDROXY-4-OXO-1,4-DIHYDROPYRIDINE DERIVATIVES AS PROTEIN-ADHESIVE ACTIVE SUBSTANCES MERCK PATENT GMBH (DE) 2015-10-29 US disclosed
US-8765967-B2 Microcapsules with UV filter activity and process for producing them DSM IP ASSETS B.V. (NE) 2014-07-01 US disclosed
US-8765967-B2 Microcapsules with UV filter activity and process for producing them DSM IP ASSETS B.V. (NE) 2014-07-01 US disclosed
US-8759428-B2 Polycarbonate compositions SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-24 US disclosed
EP-1861465-B1 CHROMOPHORE COATED METAL OXIDE PARTICLES DSM IP ASSETS BV (NL) 2010-10-13 EP disclosed
WO-2010063649-A1 NOVEL PROCESS DSM IP ASSETS B.V. (NL) 2010-06-10 WO disclosed
US-20090291107-A1 Chromophore Coated Metal Oxide Particles DSM IP ASSETS B.V. (NL) 2009-11-26 US disclosed
US-20090291107-A1 Chromophore Coated Metal Oxide Particles DSM IP ASSETS B.V. (NL) 2009-11-26 US disclosed
US-20090054586-A1 POLYCARBONATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2009-02-26 US disclosed
EP-1267819-B1 Quinoxaline derivatives, compositions containing them und use as UV-filter MERCK PATENT GMBH (DE) 2008-08-06 EP disclosed
US-20080149165-A1 LUMINESCENT SOLAR COLLECTOR GENERAL ELECTRIC COMPANY (US) 2008-06-26 US disclosed
US-20070190325-A1 Microcapsules with uv filter activity and process for producing them DSM IP ASSETS B.V. (NL) 2007-08-16 US disclosed
US-20070190325-A1 Microcapsules with uv filter activity and process for producing them DSM IP ASSETS B.V. (NL) 2007-08-16 US disclosed
EP-1373270-B1 TRICYCLIC QUINOXALINE DERIVATIVES AS A UV FILTER MERCK PATENT GMBH (DE) 2007-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150306002-A1 3-HYDROXY-4-OXO-4H-PYRAN- OR 3-HYDROXY-4-OXO-1,4-DIHYDROPYRIDINE DERIVATIVES AS PROTEIN-ADHESIVE ACTIVE SUBSTANCES S100A4, CUTA, OCIAD1 ALDH1A1 169/4885LMNA 1889/4885MAPK1 2067/4885
US-20090291107-A1 Chromophore Coated Metal Oxide Particles PPOX, MITF, MC1R ALDH1A1 1116/4885LMNA 371/4885MAPK1 2150/4885
US-20150336869-A1 DICARBOXYLIC ACID MONOMERS AND METHODS OF MAKING AND USING THE SAME PGD, CDA, PPIA ALDH1A1 902/4885LMNA 1827/4885MAPK1 3126/4885
US-20070190325-A1 Microcapsules with uv filter activity and process for producing them UACA, UROD, UMPS ALDH1A1 3001/4885LMNA 472/4885MAPK1 3748/4885
US-20220185758-A1 Oligomeric Materials for UV Blocking Applications and Methods Thereof VCL, PCNA, XRCC5 ALDH1A1 230/4885LMNA 146/4885MAPK1 4496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.