Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 17/20 | 0.44 |
| ▸ | F2 | P00734 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5534858 | 0.93 | KCNH2 (0.50) | KCNH2F10F2 | |
| SCHEMBL5534467 | 0.90 | F10 (0.48) | KCNH2F10F2 | |
| SCHEMBL5531291 | 0.89 | KCNH2 (0.61) | KCNH2F10F2 | |
| SCHEMBL5532858 | 0.83 | F10 (0.49) | KCNH2F10F2 | |
| SCHEMBL5531282 | 0.81 | F10 (0.49) | KCNH2F10F2 | |
| SCHEMBL5539613 | 0.80 | F10 (0.40) | KCNH2F10F2 | |
| SCHEMBL5534090 | 0.79 | KCNH2 (0.58) | KCNH2F10F2 | |
| SCHEMBL5536595 | 0.79 | KCNH2 (0.39) | KCNH2F10F2 | |
| SCHEMBL14345251 | 0.76 | KCNH2 (0.72) | KCNH2F10F2 | |
| SCHEMBL5532846 | 0.75 | F10 (0.49) | KCNH2F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373194-B1 | BENZAMIDE INHIBITORS OF FACTOR Xa | MILLENNIUM PHARM INC (US) | 2007-08-01 | — | — | EP | claimed |