Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33609 | 0.83 | MAPT (0.56) | HTTALDH1A1MAPTHPGDPOLB | |
| Hydrochloric Acid SCHEMBL29018535 | 0.81 | MAPT (0.54) | HTTALDH1A1MAPTHPGDPOLB | |
| SCHEMBL168120 | 0.75 | MAPT (0.57) | HTTALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL2956436 | 0.75 | MAPT (0.47) | HTTALDH1A1TSHRMAPTHPGD | |
| SCHEMBL463095 | 0.73 | ALDH1A1 (0.67) | HTTALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL18415609 | 0.73 | ALDH1A1 (0.67) | HTTALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL23295124 | 0.73 | ALDH1A1 (0.79) | ALDH1A1TSHRMAPTHPGDLMNA | |
| Toluene SCHEMBL28313052 | 0.71 | ALDH1A1 (0.65) | HTTALDH1A1TSHRHPGDLMNA | |
| SCHEMBL28335675 | 0.70 | MAPT (0.67) | HTTALDH1A1MAPTL3MBTL1 | |
| SCHEMBL22622594 | 0.70 | MAPT (0.54) | HTTALDH1A1MAPTHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220380-B2 | System and method for fabricating a three-dimensional metal object using solid free-form fabrication | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2007-05-22 | — | — | US | claimed |
| US-20050079086-A1 | System and method for fabricating a three-dimensional metal object using solid free-form fabrication | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2005-04-14 | — | — | US | claimed |