Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228289 | 0.85 | RAB9A (0.49) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| P-Xylene SCHEMBL27438753 | 0.81 | CES2 (0.59) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL33609 | 0.79 | MAPT (0.56) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Toluene SCHEMBL6691530 | 0.78 | TSHR (0.56) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29018535 | 0.78 | MAPT (0.54) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5535344 | 0.75 | HTT (0.45) | MAPTRAB9ANPC1ALDH1A1HPGD | |
| Propane SCHEMBL437272 | 0.72 | LMNA (0.59) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Alcohol SCHEMBL28089300 | 0.72 | LMNA (0.59) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL168120 | 0.72 | MAPT (0.57) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL268305 | 0.72 | TDP1 (0.67) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7758882-B2 | Composite biomaterial including anisometric calcium phosphate reinforcement particles and related methods | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2010-07-20 | — | — | US | claimed |
| US-20030031698-A1 | Composite biomaterial including anisometric calcium phosphate reinforcement particles and related methods | HAPPE SPINE, LLC | 2003-02-13 | — | — | US | claimed |
| WO-2001054746-A2 | COMPOSITE BIOMATERIAL INCLUDING ANISOMETRIC CALCIUM PHOSPHATE REINFORCEMENT PARTICLES | ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) | 2001-08-02 | — | — | WO | claimed |