Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.64 |
| ▸ | MAOA | P21397 | 3/20 | 0.64 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.64 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1069559 | 0.95 | MAOB (0.70) | MAOBMAOASCN9APARP10 | |
| SCHEMBL1071296 | 0.92 | MAOB (0.74) | MAOBMAOASCN9APARP10 | |
| SCHEMBL5684089 | 0.90 | MAOB (0.67) | MAOBMAOASCN9APARP10 | |
| SCHEMBL5680157 | 0.89 | MAOB (0.72) | MAOBMAOASCN9APARP10 | |
| SCHEMBL1070319 | 0.89 | MAOB (0.72) | MAOBMAOASCN9APARP10 | |
| SCHEMBL5684161 | 0.87 | MAOB (0.70) | MAOBMAOASCN9APARP10 | |
| SCHEMBL1070855 | 0.86 | SCN9A (0.67) | MAOBMAOASCN9APARP10 | |
| SCHEMBL1071417 | 0.85 | MAOB (0.64) | MAOBMAOASCN9APARP10 | |
| SCHEMBL5680335 | 0.82 | MAOB (0.63) | MAOBMAOASCN9A | |
| SCHEMBL1070573 | 0.80 | SCN9A (0.73) | MAOBMAOASCN9APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276046-A1 | Alpha-Aminoamide Derivatives Useful as Anti-Inflammatory Agents | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2007-11-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276046-A1 | Alpha-Aminoamide Derivatives Useful as Anti-Inflammatory Agents | IL1A, AADAT, DNPEP | MAOB 1206/4885MAOA 525/4885SCN9A 2253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.