Triaziquone

Triaziquone

SCHEMBL5537098

CCC(Cl)(Cl)OP(O)O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
HTT P42858 2/20 0.35
TP53 P04637 1/20 0.35
STAT3 P40763 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
DNMT1 P26358 1/20 0.31
LMNA P02545 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL7920385 0.82 MAPT (0.36) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL408100 0.81 TP53 (0.34) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL11350903 0.77 HTT (0.42) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL5606305 0.77 HTT (0.42) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL1650198 0.77 DNMT1 (0.43) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL11678299 0.76 MAPT (0.33) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL6387848 0.76 MAPT (0.41) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL21358774 0.75 MAPT (0.43) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL1899562 0.75 MAPT (0.36) MAPTHTTTP53STAT3SMN1; SMN2
Triaziquone SCHEMBL7783197 0.75 MAPT (0.46) MAPTHTTTP53STAT3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7211293-B2 Methods, systems and compositions for fire retarding substrates Gaston International, Inc. (US) 2007-05-01 US disclosed
US-6777469-B2 FOR USE AS FERTILIZER, TO PRODUCE RESINS, AS ODOR CONTROLLING AND AS FIRE RETARDANT AGENT BLOUNT DAVID H (US) 2004-08-17 US disclosed
US-20040121114-A1 Methods, systems and compositions for fire retarding substrates NEWORLD FIBERS, LLC 2004-06-24 US disclosed
WO-2004050980-A1 METHODS, SYSTEMS AND COMPOSITIONS FOR FIRE RETARDING SUBSTRATES NEWORLD FIBERS, LLC (US) 2004-06-17 WO disclosed
US-20030020054-A1 FLAME RETARDANT COMPOSITIONS UTILIZING AMINO CONDENSATION COMPOUNDS BLOUNT DAVID H (US) 2003-01-30 US disclosed
US-20030022959-A1 Urea condensate-sewer sludge products BLOUNT DAVID H (US) 2003-01-30 US disclosed
US-6491850-B1 FOR RIGID INSULATING POLYURETHANE FOAM BLOUNT DAVID H (US) 2002-12-10 US disclosed
US-6464903-B1 UREA CONDENSATES SUCH AS BIURET, CYANURIC ACID AND CYAMELIDE; METAL COMPOUND THAT ACCELERATES CARBONIZATION, HEAT REFLECTING COMPOUND, FILLER, SURFACTANT, WATER BLOUNT DAVID H (US) 2002-10-15 US disclosed
US-6444718-B1 CONTROLLING CONCENTRATION OF UREA IN POLYURETHANE FOAMS BLOUNT DAVID H (US) 2002-09-03 US disclosed
US-6423250-B1 FIREPROOFING ORGANIC COMPOUNDS WITH CYANURIC ACID AND CYAMELIDE AND ALDEHYDE RESIN BLOUNT DAVID H (US) 2002-07-23 US disclosed
US-6270694-B1 PRODUCT FROM REACTED UREA, ORGANIC COMPOUND, WATER, CARBONIZATION AUXILIARIES, ALDEHYDE AND FILLER BLOUNT DAVID H (US) 2001-08-07 US disclosed
US-6258298-B1 REDUCING COMBUSTIBILITY OF ORGANIC MATERIAL COMPRISING INCORPORATING AND AMINO CONDENSATION COMPOUND AND/OR COMPOSITION WITH THE ORGANIC MATERIAL, UNDER REACTION AND/OR MIXING CONDITIONS OF THE ORGANIC MATERIAL BLOUNT DAVID H (US) 2001-07-10 US disclosed
US-5854309-A Flame retardant compositions utilizing amino condensation compounds BLOUNT DAVID H (US) 1998-12-29 US disclosed
US-5788915-A Flame retardant compositions utilizing partially hydrolyzed amino condensation compounds BLOUNT DAVID H (US) 1998-08-04 US disclosed