Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.83 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.66 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2254390 | 0.91 | DGAT1 (1.00) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL2254386 | 0.91 | DGAT1 (1.00) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL2255514 | 0.83 | DGAT1 (1.00) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL2255509 | 0.83 | DGAT1 (1.00) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL2258213 | 0.80 | DGAT1 (1.00) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL2258211 | 0.80 | DGAT1 (1.00) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL180883 | 0.79 | DGAT1 (1.00) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL2252856 | 0.77 | DGAT1 (1.00) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL2252864 | 0.77 | DGAT1 (1.00) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL4467593 | 0.76 | DGAT1 (0.64) | DGAT1SOAT1FAAHCHRM2DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108602-A1 | Carbamoyl Compounds as DGAT1 Inhibitors 190 | ASTRAZENECA AB (SE) | 2012-05-03 | — | — | US | disclosed |
| US-20120108602-A1 | Carbamoyl Compounds as DGAT1 Inhibitors 190 | ASTRAZENECA AB (SE) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108602-A1 | Carbamoyl Compounds as DGAT1 Inhibitors 190 | DGAT1, DGAT2, SOAT1 | DGAT1 1/4885SOAT1 3/4885FAAH 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.