Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.56 |
| ▸ | PGR | P06401 | 3/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RORA | P35398 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14496173 | 1.00 | NR3C1 (0.56) | NR3C1PGRARHCRTR1GAA | |
| SCHEMBL5537989 | 1.00 | NR3C1 (0.56) | NR3C1PGRARHCRTR1GAA | |
| SCHEMBL5537996 | 1.00 | NR3C1 (0.56) | NR3C1PGRARHCRTR1GAA | |
| SCHEMBL14496171 | 0.88 | NR3C1 (0.44) | NR3C1PGRARHCRTR1GAA | |
| SCHEMBL5540492 | 0.88 | NR3C1 (0.44) | NR3C1PGRARHCRTR1GAA | |
| SCHEMBL5540487 | 0.88 | NR3C1 (0.44) | NR3C1PGRARHCRTR1GAA | |
| SCHEMBL5540483 | 0.88 | NR3C1 (0.44) | NR3C1PGRARHCRTR1GAA | |
| SCHEMBL14496176 | 0.84 | NR3C1 (0.51) | NR3C1PGRARGAAALDH1A1 | |
| SCHEMBL5546340 | 0.84 | NR3C1 (0.51) | NR3C1PGRARGAAALDH1A1 | |
| SCHEMBL5533618 | 0.80 | NR3C1 (0.55) | NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129359-A1 | Tetrahydronaphthalene derivatives, processes for their preparation and their use as antiinflammatory agents | SCHERING AG (DE) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129359-A1 | Tetrahydronaphthalene derivatives, processes for their preparation and their use as antiinflammatory agents | TNF, IL1B, PTGS1 | NR3C1 190/4885PGR 2358/4885AR 2736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.