⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL16569295 | 0.88 | NOS1 (0.33) | — | |
| SCHEMBL27532414 | 0.81 | — | — | |
| SCHEMBL28140448 | 0.81 | — | — | |
| SCHEMBL2020872 | 0.78 | TSHR (0.35) | — | |
| SCHEMBL6006 | 0.77 | SLC6A2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL28224572 | 0.76 | — | — | |
| SCHEMBL20025517 | 0.73 | PAOX (0.34) | — | |
| SCHEMBL28140457 | 0.73 | DGAT1 (0.35) | — | |
| SCHEMBL6005 | 0.73 | SLC6A2 (0.46) | — | |
| SCHEMBL22899941 | 0.73 | SLC6A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110088087-B | Tetrahydropyridine derivatives and their use as antibacterial agents | 东亚ST株式会社 | 2022-08-09 | — | — | CN | claimed |
| CN-110088087-A | TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | 东亚ST株式会社 | 2019-08-02 | — | — | CN | claimed |
| WO-2019038362-A1 | ANTIBACTERIAL PYRROLOIMIDAZOLONES | IDORSIA PHARMACEUTICALS LTD (CH) | 2019-02-28 | — | — | WO | claimed |
| CN-105829288-B | Antibacterial 1H- indazole and 1H- indole derivatives | 爱杜西亚药品有限公司 | 2019-01-15 | — | — | CN | claimed |
| EP-3083567-A1 | ANTIBACTERIAL 1H-INDAZOLE AND 1H-INDOLE DERIVATIVES | Actelion Pharmaceuticals Ltd (CH) | 2016-10-26 | — | — | EP | claimed |
| EP-3044211-A1 | ANTIBACTERIAL 2H-INDAZOLE DERIVATIVES | Actelion Pharmaceuticals Ltd (CH) | 2016-07-20 | — | — | EP | claimed |
| WO-2015091741-A1 | ANTIBACTERIAL 1H-INDAZOLE AND 1H-INDOLE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2015-06-25 | — | — | WO | claimed |
| WO-2015036964-A1 | ANTIBACTERIAL 2H-INDAZOLE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2015-03-19 | — | — | WO | claimed |
| CN-101370812-A | Fused heterocyclic compound | TAKEDA PHARMACEUTICAL (JP) | 2009-02-18 | — | — | CN | claimed |
| CN-110088087-B | Tetrahydropyridine derivatives and their use as antibacterial agents | 东亚ST株式会社 | 2022-08-09 | — | — | CN | disclosed |
| CN-110088087-A | TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | 东亚ST株式会社 | 2019-08-02 | — | — | CN | disclosed |
| WO-2019038362-A1 | ANTIBACTERIAL PYRROLOIMIDAZOLONES | IDORSIA PHARMACEUTICALS LTD (CH) | 2019-02-28 | — | — | WO | disclosed |
| CN-105829288-B | Antibacterial 1H- indazole and 1H- indole derivatives | 爱杜西亚药品有限公司 | 2019-01-15 | — | — | CN | disclosed |
| CN-108368053-A | Substituted benzazepine derivatives as antibacterial compounds | 葛兰素史密斯克莱知识产权发展有限公司 | 2018-08-03 | — | — | CN | disclosed |
| WO-2012137094-A1 | ISOXAZOLE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2012-10-11 | — | — | WO | disclosed |
| WO-2012120397-A1 | FLUORO-PYRIDINONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| US-20120202777-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | BROWN MATTHEW FRANK (US) | 2012-08-09 | — | — | US | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |
| CN-101370812-A | Fused heterocyclic compound | TAKEDA PHARMACEUTICAL (JP) | 2009-02-18 | — | — | CN | disclosed |