SCHEMBL5538207

SCHEMBL5538207

C=NC(=O)c1cccc(C(N)=O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 11/20 0.57
TSHR P16473 2/20 0.46
POLB P06746 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C19 P33261 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PARP15 Q460N3 4/20 0.44
PARP10 Q53GL7 4/20 0.44
PARP14 Q460N5 3/20 0.44
TNKS O95271 1/20 0.44
TNKS2 Q9H2K2 1/20 0.44
PARP2 Q9UGN5 1/20 0.44
FURIN P09958 1/20 0.43
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29496476 1.00 PARP1 (0.57) PARP1TSHRPOLBCYP3A4MAPT
Cyclohexane SCHEMBL9858532 0.94 PARP1 (0.52) PARP1TSHRPOLBCYP3A4MAPT
SCHEMBL31021028 0.82 PARP1 (0.73) PARP1TSHRPOLBCYP3A4MAPT
SCHEMBL36694 0.82 PARP1 (0.73) PARP1TSHRPOLBCYP3A4MAPT
Methane SCHEMBL688609 0.80 PARP1 (0.70) PARP1TSHRPOLBCYP3A4MAPT
Hydrochloric Acid SCHEMBL1367509 0.80 PARP1 (0.70) PARP1TSHRPOLBCYP3A4MAPT
Ammonia Solution, Strong SCHEMBL9121446 0.80 PARP1 (0.70) PARP1TSHRPOLBCYP3A4MAPT
Water SCHEMBL7768285 0.80 PARP1 (0.70) PARP1TSHRPOLBCYP3A4MAPT
SCHEMBL14400735 0.80 PARP1 (0.53) PARP1TSHRPOLBCYP3A4MAPT
SCHEMBL7174188 0.79 PARP1 (0.52) PARP1TSHRPOLBCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070155877-A1 Polyamide resin composition E. I. DU PONT DE NEMOURS AND COMPANY 2007-07-05 US claimed
EP-4337441-B1 IMPROVED METHOD FOR FORMING THERMOPLASTIC ADDITIVE MANUFACTURING POWDERS LUMAS POLYMERS LLC (US) 2025-11-26 EP disclosed
US-12180343-B2 Thermoplastic polymers and method to make them LUMAS POLYMERS LLC (US) 2024-12-31 US disclosed
WO-2024226710-A1 METHOD TO FORM COMPOSITE PARTICLES AND ARTICLES MADE THEREFROM Jabil Inc. (US) 2024-10-31 WO disclosed
WO-2024215596-A1 POLYMER CRYSTALLIZATION METHOD AND ADDITIVE MANUFACTURED POWDERS MADE THEREFROM Jabil Inc. (US) 2024-10-17 WO disclosed
EP-4337441-A1 IMPROVED METHOD FOR FORMING THERMOPLASTIC ADDITIVE MANUFACTURING POWDERS Jabil Inc. (US) 2024-03-20 EP disclosed
WO-2024044062-A1 THERMOPLASTIC PARTICULATES AND METHOD TO MAKE THEM Jabil Inc. (US) 2024-02-29 WO disclosed
US-11845833-B2 Method for forming thermoplastic additive manufacturing powders Jabil Inc. (US) 2023-12-19 US disclosed
WO-2023211780-A9 SPHERICAL PARTICLES FOR ADDITIVE MANUFACTURING Jabil Inc. (US) 2023-12-07 WO disclosed
WO-2023211780-A1 SPHERICAL PARTICLES FOR ADDITIVE MANUFACTURING Jabil Inc. (US) 2023-11-02 WO disclosed
EP-0595886-A1 GRAFT POLYMERS FOR USE IN ENGINEERING THERMOPLASTIC BLENDS EXXON CHEMICAL PATENTS INC. (US) 1994-05-11 EP disclosed
WO-1993002140-A1 GRAFT POLYMERS FOR USE IN ENGINEERING THERMOPLASTIC BLENDS EXXON CHEMICAL PATENTS INC. (US) 1993-02-04 WO disclosed
EP-0395414-A1 Crystalline polyphtalamide composition having improved heat resistance properties AMOCO CORPORATION (US) 1990-10-31 EP disclosed
EP-0361636-A2 Polyamide-polyarylene sulfide blends AMOCO CORPORATION (US) 1990-04-04 EP disclosed
EP-0291833-A1 Stabilised polyamide mouldings reinforced with glass fibres BAYER AG (DE) 1988-11-23 EP disclosed
EP-0282730-A1 Glass fibre-reinforced polyamide moulding compositions with an increased salt and weather resistance BAYER AG (DE) 1988-09-21 EP disclosed
EP-0279578-A1 Moldable thermoplastic polyamide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-08-24 EP disclosed
EP-0270146-A1 Copolyamide and a process for the preparation thereof DSM N.V. (NL) 1988-06-08 EP disclosed
EP-0262796-A2 Resin compositons and their manufacturing method TORAY INDUSTRIES, INC. (JP) 1988-04-06 EP disclosed
EP-0234819-A2 Thermoplastic resin compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-02 EP disclosed