Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 10/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29496476 | 0.94 | PARP1 (0.57) | PARP1PARP15PARP10TSHRPOLB | |
| SCHEMBL5538207 | 0.94 | PARP1 (0.57) | PARP1PARP15PARP10TSHRPOLB | |
| Cyclohexane SCHEMBL180075 | 0.84 | PARP1 (0.64) | PARP1GAAPARP15PARP10BRD4 | |
| SCHEMBL2831672 | 0.84 | PARP1 (0.64) | PARP1GAAPARP15PARP10BRD4 | |
| Cyclohexane SCHEMBL9229438 | 0.82 | PARP1 (0.61) | PARP1GAAPARP15PARP10BRD4 | |
| Cyclohexane SCHEMBL10592083 | 0.81 | PARP10 (0.43) | PARP1PARP15PARP10TSHRPOLB | |
| Terephthalamide SCHEMBL4985044 | 0.81 | PARP1 (0.59) | PARP1GAAPARP15PARP10BRD4 | |
| SCHEMBL31021028 | 0.78 | PARP1 (0.73) | PARP1PARP15PARP10TSHRPOLB | |
| SCHEMBL36694 | 0.78 | PARP1 (0.73) | PARP1PARP15PARP10TSHRPOLB | |
| Hydrochloric Acid SCHEMBL1367509 | 0.76 | PARP1 (0.70) | PARP1PARP15PARP10TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301003-B1 | MODIFIED POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1991-01-02 | — | — | EP | disclosed |
| EP-0301004-A1 | POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1989-02-01 | — | — | EP | disclosed |
| EP-0301003-A1 | MODIFIED POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS. | GEN ELECTRIC (US) | 1989-02-01 | — | — | EP | disclosed |
| WO-1988006172-A1 | MODIFIED POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1988-08-25 | — | — | WO | disclosed |
| WO-1988006168-A1 | POLYPHENYLENE ETHER-POLYAMIDE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1988-08-25 | — | — | WO | disclosed |