Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 5/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | MTTP | P55157 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364389 | 0.94 | ALDH1A1 (0.34) | ALDH1A1HTTRXFP1DHFRTRPV4 | |
| SCHEMBL3729050 | 0.91 | SMO (0.42) | RXFP1PPARGPPARDPPARANR1H4 | |
| SCHEMBL1682996 | 0.90 | DHFR (0.37) | ALDH1A1HTTRXFP1TACR1DHFR | |
| SCHEMBL3734668 | 0.87 | PPARG (0.38) | ALDH1A1HTTRXFP1PPARGPPARD | |
| SCHEMBL3726645 | 0.87 | RXFP1 (0.40) | ALDH1A1HTTRXFP1SMN1; SMN2PPARG | |
| Granotapide SCHEMBL1484041 | 0.87 | MTTP (0.44) | MTTP | |
| SCHEMBL3726274 | 0.86 | NPSR1 (0.38) | ALDH1A1HTTRXFP1PPARGPPARD | |
| SCHEMBL3725220 | 0.86 | RXFP1 (0.43) | ALDH1A1RXFP1SMN1; SMN2PPARGPPARD | |
| SCHEMBL3734637 | 0.86 | ALDH1A1 (0.38) | ALDH1A1HTTRXFP1DHFRPLK1 | |
| SCHEMBL3730910 | 0.86 | ALDH1A1 (0.38) | ALDH1A1HTTRXFP1DHFRPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806149-A1 | SOLID MEDICINAL PREPARATION IMPROVED IN SOLUBILITY AND STABILITY AND PROCESS FOR PRODUCING THE SAME | Japan Tobacco, Inc. (JP) | 2007-07-11 | — | — | EP | disclosed |