Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL2329719 | 0.90 | TP53 (0.73) | TP53TSHRSLC7A5PMP22KDM4E | |
| Lactic Acid SCHEMBL8948925 | 0.88 | TP53 (0.69) | TP53TSHRSLC7A5PMP22KDM4E | |
| Lactic Acid SCHEMBL27678051 | 0.88 | TP53 (0.69) | TP53TSHRSLC7A5PMP22KDM4E | |
| Lactic Acid SCHEMBL28286519 | 0.88 | TP53 (0.69) | TP53TSHRSLC7A5PMP22KDM4E | |
| Lactic Acid SCHEMBL6394823 | 0.88 | TP53 (0.69) | TP53TSHRSLC7A5PMP22KDM4E | |
| Lactic Acid SCHEMBL1584321 | 0.88 | TP53 (0.69) | TP53TSHRSLC7A5PMP22KDM4E | |
| Lactic Acid SCHEMBL17181727 | 0.88 | TP53 (0.69) | TP53TSHRSLC7A5PMP22KDM4E | |
| Lactic Acid SCHEMBL27886196 | 0.88 | TP53 (0.69) | TP53TSHRSLC7A5PMP22KDM4E | |
| Lactic Acid SCHEMBL28292938 | 0.88 | TP53 (0.69) | TP53TSHRSLC7A5PMP22KDM4E | |
| Lactic Acid SCHEMBL3446640 | 0.88 | TP53 (0.69) | TP53TSHRSLC7A5PMP22KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219197-A1 | Pyridyl alkene and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | ASTELLAS PHARMA GMBH (DE) | 2007-09-20 | — | — | US | claimed |
| JP-53149945-A | — | — | None | — | — | JP | disclosed |
| CN-103930976-B | Composition for polishing and employ its Ginding process and the manufacture method of substrate | 福吉米株式会社 | 2016-08-17 | — | — | CN | disclosed |
| CN-1167678-C | Novel vitamin D analogues | ������˹ҩƷ��˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1372544-A | Novel vitamin D analogues | LEO PHARM PROD LTD (DK) | 2002-10-02 | — | — | CN | disclosed |
| CN-1105666-A | Novel diazabicycloalkenes and processes for the preparation thereof | KOREA RES INST CHEM TECH (KR) | 1995-07-26 | — | — | CN | disclosed |
| EP-0248554-B1 | HETEROCYCLIC COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-03 | — | — | EP | disclosed |
| CN-1017428-B | HETEROCYCLIC COMPOUNDS | ICI PLC (GB) | 1992-07-15 | — | — | CN | disclosed |
| CN-87104533-A | Heterogeneous ring compound | — | 1988-01-20 | — | — | CN | disclosed |
| EP-0248554-A2 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-12-09 | — | — | EP | disclosed |
| JP-S53149945-A | PREPARATION OF ALPHA-PHENYLPROPIONIC ACID DERIVATIVES | MITSUI TOATSU CHEM INC | 1978-12-27 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219197-A1 | Pyridyl alkene and pyridyl alkine- acid amides as cytostatics and immuno-suppressives | NFATC1, PDCD1, ACIN1 | TP53 54/4885TSHR 3222/4885CA2 2001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.