Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 9/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.38 |
| ▸ | CDK9 | P50750 | 8/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2993969 | 0.91 | IGF1R (0.39) | CCNT1CDK9IGF1R | |
| SCHEMBL2986604 | 0.90 | IGF1R (0.44) | SUV39H2CCNT1CDK9IGF1R | |
| SCHEMBL2982715 | 0.90 | CCNT1 (0.42) | SUV39H2CCNT1CDK9 | |
| SCHEMBL2990025 | 0.88 | CCNT1 (0.45) | CCNT1CDK9IGF1R | |
| SCHEMBL5535776 | 0.86 | IGF1R (0.41) | CCNT1CDK9IGF1R | |
| SCHEMBL2987134 | 0.86 | CDK9 (0.39) | CCNT1CDK9IGF1R | |
| Hydrochloric Acid SCHEMBL2984613 | 0.85 | IGF1R (0.41) | CCNT1CDK9IGF1R | |
| SCHEMBL2995039 | 0.85 | IGF1R (0.42) | CCNT1CDK9IGF1R | |
| SCHEMBL5533445 | 0.85 | IGF1R (0.42) | CCNT1CDK9IGF1R | |
| SCHEMBL5529651 | 0.85 | CCNT1 (0.43) | SUV39H2CCNT1CDK9IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799691-A1 | NOVEL BIS-AZAINDOLE DERIVATIVES, PREPARATION AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006037875-A1 | NOVEL BIS-AZAINDOLE DERIVATIVES, PREPARATION AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2006-04-13 | — | — | WO | disclosed |