Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5538961 | 1.00 | CHRM1 (0.35) | CHRM1LMNAALDH1A1KCNH2USP2 | |
| SCHEMBL5540324 | 1.00 | CHRM1 (0.35) | CHRM1LMNAALDH1A1KCNH2USP2 | |
| SCHEMBL6010853 | 0.85 | ALDH1A1 (0.41) | CHRM1LMNAALDH1A1KCNH2 | |
| SCHEMBL5535946 | 0.85 | ALDH1A1 (0.41) | CHRM1LMNAALDH1A1KCNH2 | |
| SCHEMBL6010762 | 0.85 | ALDH1A1 (0.41) | CHRM1LMNAALDH1A1KCNH2 | |
| SCHEMBL6010863 | 0.84 | CHRM1 (0.33) | CHRM1KCNH2 | |
| SCHEMBL6010771 | 0.84 | CHRM1 (0.33) | CHRM1KCNH2 | |
| SCHEMBL6010766 | 0.84 | CHRM1 (0.33) | CHRM1KCNH2 | |
| SCHEMBL14966228 | 0.80 | KCNH2 (0.37) | CHRM1LMNAALDH1A1KCNH2KMT2A | |
| SCHEMBL5548049 | 0.79 | SIGMAR1 (0.39) | CHRM1ALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |