Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS12 | P56730 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2721359 | 0.88 | MAPT (0.61) | PRSS12 | |
| SCHEMBL5538881 | 0.86 | PRSS12 (0.70) | PRSS12 | |
| SCHEMBL4651922 | 0.85 | MAPT (0.78) | PRSS12 | |
| SCHEMBL5536880 | 0.84 | PRSS12 (0.81) | PRSS12 | |
| SCHEMBL6349922 | 0.84 | PRSS12 (0.78) | PRSS12 | |
| SCHEMBL5534180 | 0.83 | PRSS12 (0.71) | PRSS12 | |
| SCHEMBL6351071 | 0.82 | PRSS12 (0.69) | PRSS12 | |
| SCHEMBL2733479 | 0.82 | PRSS12 (1.00) | PRSS12 | |
| SCHEMBL2724943 | 0.82 | PRSS12 (0.73) | PRSS12 | |
| SCHEMBL2732413 | 0.81 | PRSS12 (0.68) | PRSS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059442-A2 | NEUROTRYPSIN INHIBITORS | NEUROTUNE AG (CH) | 2012-05-10 | — | — | WO | disclosed |