Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS12 | P56730 | 14/20 | 0.69 |
| ▸ | F10 | P00742 | 5/20 | 0.62 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6349922 | 0.90 | PRSS12 (0.78) | PRSS12F10 | |
| SCHEMBL6352936 | 0.83 | AKR1C2 (0.74) | — | |
| SCHEMBL5539074 | 0.82 | PRSS12 (0.70) | PRSS12 | |
| SCHEMBL15718673 | 0.82 | PRSS12 (1.00) | PRSS12F10 | |
| SCHEMBL16562251 | 0.79 | MAPT (0.65) | PRSS12F10PIN1 | |
| SCHEMBL6352294 | 0.79 | AKR1C2 (0.70) | — | |
| SCHEMBL14075244 | 0.78 | AKR1C2 (0.66) | — | |
| SCHEMBL6591033 | 0.78 | F10 (0.88) | PRSS12F10 | |
| SCHEMBL4651922 | 0.78 | MAPT (0.78) | PRSS12F10 | |
| SCHEMBL6353526 | 0.77 | AKR1C2 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | PRSS12 3257/4885F10 2427/4885PIN1 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.