SCHEMBL5539424

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5545718	0.95	MAOB (0.33)	MAOBAHRALDH1A1NPSR1CYP1A2
	SCHEMBL5535500	0.94	MAOB (0.32)	MAOBAHRALDH1A1NPSR1CYP1A2
	SCHEMBL5534619	0.90	AHR (0.35)	MAOBAHRALDH1A1NPSR1CYP1A2
	SCHEMBL5545899	0.83	ALDH1A1 (0.32)	ALDH1A1KDM4EMAPTHSD17B10NPC1
	SCHEMBL5541566	0.83	CTRC (0.36)	ALDH1A1HPGDDAO
	SCHEMBL5542932	0.83	MAOB (0.40)	MAOBALDH1A1NOTUMALOX5NPC1
	SCHEMBL5540563	0.82	AHR (0.38)	MAOBAHRALDH1A1NPSR1CYP1A2
	SCHEMBL5540626	0.79	SIRT2 (0.32)	ALDH1A1KDM4EMAPTHSD17B10NPC1
	SCHEMBL5544415	0.78	MAOB (0.39)	MAOBALDH1A1NOTUMALOX5NPC1
	SCHEMBL5535282	0.78	CTRC (0.35)	ALDH1A1HPGDDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.