SCHEMBL5539445

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10863239	0.98	MGLL (0.51)	MPOSLC6A4MGLLTAAR1EP300
	SCHEMBL10719846	0.98	MGLL (0.51)	MPOSLC6A4MGLLTAAR1EP300
	SCHEMBL11373976	0.98	MGLL (0.51)	MPOSLC6A4MGLLTAAR1EP300
	SCHEMBL647126	0.98	MGLL (0.51)	MPOSLC6A4MGLLTAAR1EP300
	Ammonia Solution, Strong SCHEMBL29482611	0.96	MGLL (0.50)	MPOSLC6A4MGLLTAAR1EP300
	SCHEMBL5538659	0.94	MPO (0.50)	MPOSLC6A4MGLLTAAR1EP300
	Oxirane SCHEMBL10719749	0.90	MGLL (0.45)	MPOSLC6A4MGLLTAAR1EP300
	SCHEMBL5543573	0.86	TAAR1 (0.54)	MPOSLC6A4TAAR1HSPA5ACHE
	SCHEMBL19431545	0.85	IAPP (0.46)	MPOSLC6A4MGLLTAAR1EP300
	SCHEMBL14562493	0.83	EP300 (0.69)	MPOSLC6A4MGLLTAAR1EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.