SCHEMBL5539716

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5540098	0.87	ERCC1 (0.52)	KMT2APOLBDRD3KCNH2LMNA
	SCHEMBL5539132	0.86	HSD11B1 (0.46)	KMT2APOLBCYP2D6CYP2C9CYP2C19
	SCHEMBL5547302	0.86	RAB9A (0.54)	KMT2APOLBCYP2D6CYP2C9CYP2C19
	SCHEMBL5545330	0.83	GAA (0.51)	KMT2APOLBCYP2C19LMNAMEN1
	SCHEMBL5544692	0.81	CHRM3 (0.53)	CYP2D6CYP2C9CYP2C19DRD3CYP3A4
	SCHEMBL29450073	0.80	KMT2A (0.76)	KMT2APOLBCYP2D6CYP2C9CYP2C19
	SCHEMBL16416392	0.80	KMT2A (0.76)	KMT2APOLBCYP2D6CYP2C9CYP2C19
	SCHEMBL5542390	0.79	RAB9A (0.51)	KMT2ADRD3KCNH2MEN1HDAC1
	SCHEMBL22252441	0.76	POLB (0.65)	KMT2APOLBCYP2D6CYP2C9CYP2C19
	SCHEMBL5535021	0.73	CYP2D6 (0.69)	KMT2APOLBCYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.