⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14571054 | 0.87 | ALDH1A1 (0.39) | — | |
| SCHEMBL5533138 | 0.84 | — | — | |
| SCHEMBL14651377 | 0.81 | — | — | |
| SCHEMBL2625118 | 0.79 | — | — | |
| SCHEMBL239695 | 0.79 | — | — | |
| SCHEMBL1253311 | 0.77 | — | — | |
| SCHEMBL5538223 | 0.74 | — | — | |
| SCHEMBL2055290 | 0.74 | — | — | |
| SCHEMBL18455877 | 0.74 | CA12 (0.32) | — | |
| Propane SCHEMBL11542346 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556148-B2 | N-cyanomethylamides as inhibitors of janus kinase | CADILA HEALTHCARE LIMITED (IN) | 2017-01-31 | — | — | US | disclosed |
| US-9556148-B2 | N-cyanomethylamides as inhibitors of janus kinase | CADILA HEALTHCARE LIMITED (IN) | 2017-01-31 | — | — | US | disclosed |
| US-20160176849-A1 | N-CYANOMETHYLAMIDES AS INHIBITORS OF JANUS KINASE | CADILA HEALTHCARE LIMITED (IN) | 2016-06-23 | — | — | US | disclosed |
| US-20160176849-A1 | N-CYANOMETHYLAMIDES AS INHIBITORS OF JANUS KINASE | CADILA HEALTHCARE LIMITED (IN) | 2016-06-23 | — | — | US | disclosed |
| US-8173802-B2 | Method for producing piperidin-4-one derivative | NIPPON SODA CO., LTD. (JP) | 2012-05-08 | — | — | US | disclosed |
| EP-1751199-B1 | NOVEL PHENOLIC RESINS | ANGUS CHEMICAL (US) | 2010-11-24 | — | — | EP | disclosed |
| EP-2058303-B1 | METHOD FOR PRODUCING A PIPERIDIN-4-ONE-DERIVATIVE | NIPPON SODA CO (JP) | 2010-08-18 | — | — | EP | disclosed |
| US-20100004455-A1 | Method for producing piperidin-4-one derivative | NIPPON SODA CO., LTD. (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-2058303-A1 | METHOD FOR PRODUCING PIPERIDIN-4-ONE-DERIVATIVE | Nippon Soda Co., Ltd. (JP) | 2009-05-13 | — | — | EP | disclosed |