Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855931 | 0.80 | SLC6A3 (0.41) | PTGDR2GABRR1MEN1KMT2AALDH1A1 | |
| SCHEMBL25424926 | 0.80 | HPGD (0.38) | PTGDR2GABRR1GCKALDH1A1HPGD | |
| SCHEMBL15826080 | 0.78 | GCK (0.36) | PTGDR2GABRR1GCKALDH1A1HPGD | |
| SCHEMBL11922677 | 0.77 | PTGDR2 (0.40) | PTGDR2GABRR1MEN1KMT2AALDH1A1 | |
| SCHEMBL2666129 | 0.77 | CYP1A2 (0.42) | PTGDR2GCKMEN1KMT2AALDH1A1 | |
| SCHEMBL14215474 | 0.77 | ALDH1A1 (0.40) | PTGDR2GABRR1MEN1KMT2AALDH1A1 | |
| SCHEMBL14215510 | 0.77 | PTGDR2 (0.43) | PTGDR2GABRR1MEN1KMT2AALDH1A1 | |
| SCHEMBL5521343 | 0.77 | GCK (0.36) | PTGDR2GABRR1GCKALDH1A1MAPT | |
| SCHEMBL27837189 | 0.74 | PTGDR2 (0.62) | PTGDR2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11923125 | 0.73 | PTGDR2 (0.37) | PTGDR2GABRR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |