SCHEMBL5540199

SCHEMBL5540199

N#CNc1ccc(F)cc1F.Nc1ccc(F)cc1F

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
HDAC1 Q13547 3/20 0.38
LMNA P02545 1/20 0.37
SOS1 Q07889 1/20 0.36
HTT P42858 2/20 0.36
CYP2C19 P33261 2/20 0.34
HDAC6 Q9UBN7 1/20 0.34
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
ALOX12 P18054 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
RECQL P46063 1/20 0.33
CYP2D6 P10635 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29595875 0.77
SCHEMBL11425 0.77
Cyanide SCHEMBL27761725 0.75 ALDH1A1 (0.85) ALDH1A1HDAC1HTTHDAC6TDP1
Methane SCHEMBL22289605 0.74 ALDH1A1 (0.94) ALDH1A1HDAC1HTTHDAC6TDP1
Hydrochloric Acid SCHEMBL7125109 0.74 ALDH1A1 (0.94) ALDH1A1HDAC1HTTHDAC6TDP1
Hydrochloric Acid SCHEMBL3851075 0.74 ALDH1A1 (0.94) ALDH1A1HDAC1HTTHDAC6TDP1
Fluoride SCHEMBL29165726 0.74 ALDH1A1 (0.94) ALDH1A1HDAC1HTTHDAC6TDP1
SCHEMBL9535914 0.71 MAP2K1 (0.47) ALDH1A1HDAC1SOS1CYP2C19NPC1
SCHEMBL3185380 0.71 NPC1 (0.42) ALDH1A1LMNAHTTMEN1MAPT
SCHEMBL2096174 0.70 HTT (0.46) ALDH1A1SOS1HTTCYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007126262-A1 ANION RECEPTOR, AND ELECTROLYTE USING THE SAME KYUNGWON ENTERPRISE CO., LTD. (KR) 2007-11-08 WO disclosed