SCHEMBL5540359

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14613741	0.98	KAT8 (0.50)	KAT8PPARALPLLIPGESR1
	SCHEMBL5542995	0.95	NPC1 (0.49)	KAT8PPARAESR1PLAU
	SCHEMBL5541800	0.88	CNR1 (0.52)	ESR1PLAU
	SCHEMBL10523809	0.86	KAT8 (0.50)	KAT8PPARALPLLIPGESR1
	SCHEMBL11852540	0.82	CYP1A2 (0.50)	LPLLIPGESR1ADRA2AADORA3
	SCHEMBL3359160	0.81	CYP1A2 (0.53)	ESR1PLAU
	SCHEMBL14051803	0.81	PTGS2 (0.51)	PPARAESR1ADRA2AADORA3TACR2
	SCHEMBL11230398	0.81	S1PR1 (0.56)	LPLLIPG
	SCHEMBL5540351	0.81	S1PR1 (0.45)	KAT8PPARALPLLIPGALDH1A1
	SCHEMBL11852534	0.81	LPL (0.44)	LPLLIPGESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.