SCHEMBL554052

SCHEMBL554052

C=CC(=O)NCCSC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8017853 0.88 ZDHHC20 (0.46)
SCHEMBL10431762 0.88 ZDHHC20 (0.58)
SCHEMBL22861299 0.82 ALDH1A1 (0.54)
SCHEMBL106883 0.82 TSHR (0.54)
SCHEMBL31224580 0.80 TSHR (0.52)
SCHEMBL16257689 0.79 ZDHHC20 (0.48)
SCHEMBL8014476 0.79 ZDHHC20 (0.53)
SCHEMBL19519587 0.78
SCHEMBL10952688 0.78 TSHR (0.68)
SCHEMBL167051 0.78 TSHR (0.68)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024129968-A1 INJECTABLE COMPOSITIONS FOR TREATING JOINT CONDITIONS OHIO STATE INNOVATION FOUNDATION (US) 2024-06-20 WO claimed
EP-3920986-A1 ANTIOXIDANT-RELEASING VITREOUS SUBSTITUTES AND USES THEREOF Ohio State Innovation Foundation (US) 2021-12-15 EP claimed
US-20210324125-A1 POLYMERS AND METHODS FOR OPHTHALMIC APPLICATIONS KEY MEDICAL TECH INC (US) 2021-10-21 US claimed
WO-2020163872-A1 ANTIOXIDANT-RELEASING VITREOUS SUBSTITUTES AND USES THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2020-08-13 WO claimed
US-20200087433-A1 NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS KEY MEDICAL TECH INC (US) 2020-03-19 US claimed
US-10421830-B2 Nanohybrid polymers for ophthalmic applications KEY MEDICAL TECHNOLOGIES, INC. (US) 2019-09-24 US claimed
US-20190119425-A1 Polymers and Methods for Ophthalmic Applications KEY MEDICAL TECH INC (US) 2019-04-25 US claimed
EP-3207076-A1 POLYMERS AND METHODS FOR OPTHALMIC APPLICATIONS Key Medical Technologies, Inc. (US) 2017-08-23 EP claimed
WO-2016061457-A1 POLYMERS AND METHODS FOR OPTHALMIC APPLICATIONS KEY MEDICAL TECHNOLOGIES, INC. (US) 2016-04-21 WO claimed
US-20150274869-A1 NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS KEY MEDICAL TECHNOLOGIES, INC. 2015-10-01 US claimed
US-8153156-B2 Hydrogel nanocompsites for ophthalmic applications THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS (US) 2012-04-10 US claimed
US-20120035337-A1 NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS KEY MEDICAL TECHNOLOGIES, INC. (US) 2012-02-09 US claimed
WO-2011079380-A1 TRANSPARENT BACTERIAL CELLULOSE NANOCOMPOSITE HYDROGELS AXCELON BIOPOLYMERS CORPORATION (CA) 2011-07-07 WO claimed
US-20110144228-A1 HYDROGEL NANOCOMPOSITES FOR INTRAOCULAR LENS APPLICATONS WASHINGTON UNIVERSITY 2011-06-16 US claimed
US-20100261858-A1 NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS KEY MEDICAL TECHNOLOGIES, INC. (US) 2010-10-14 US claimed
US-20070269488-A1 Hydrogel Nanocompsites for Ophthalmic Applications THE WASHINGTON UNIVERSITY IN ST. LOUIS 2007-11-22 US claimed
US-20060122349-A1 Making high refractive index copolymer by sonicating mixture of carbazole or naphthyl moiety, naphthyl group monomer, hydrophobic monomer, hydrophillic monomer, and crosslinker; soft, optically transparent, high refractive index materials particularly suited for use in intraocular, contact lenses KEY MEDICAL TECHNOLOGIES, INC. (US) 2006-06-08 US claimed
EP-1660153-A2 HYDROGEL NANOCOMPSITES FOR OPHTHALMIC APPLICATIONS The United States of America as represented by the Department of Veterans Affairs (US) 2006-05-31 EP claimed
WO-2005023331-A2 HYDROGEL NANOCOMPSITES FOR OPHTHALMIC APPLICATIONS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) 2005-03-17 WO claimed
US-20040156880-A1 Reversible hydrogel systems and methods therefor DEPARTMENT OF VETERANS AFFAIRS, THE 2004-08-12 US claimed