SCHEMBL5540653

SCHEMBL5540653

[O]CCCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.55
FDFT1 P37268 4/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC1 Q13547 1/20 0.51
MMP12 P39900 4/20 0.48
ABCC4 O15439 1/20 0.48
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
TSHR P16473 1/20 0.48
PTGS1 P23219 1/20 0.48
HTT P42858 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
MMP13 P45452 3/20 0.47
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP14 P50281 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5546674 0.93 HDAC2 (0.56) FFAR1FDFT1HDAC2HDAC1MMP12
SCHEMBL5534572 0.91 HDAC2 (0.57) FFAR1FDFT1HDAC2HDAC1MMP12
SCHEMBL5540190 0.91 HDAC2 (0.57) FFAR1FDFT1HDAC2HDAC1MMP12
SCHEMBL5539870 0.86 FFAR1 (0.59) FFAR1FDFT1HDAC2MMP12ABCC4
SCHEMBL1544 0.85 ALDH1A1 (0.57) HDAC2HDAC1
SCHEMBL30869989 0.85 HDAC2 (0.60) FFAR1FDFT1HDAC2HDAC1ABCC4
SCHEMBL9826765 0.83 HTR2A (0.62) FFAR1FDFT1HDAC2HDAC1MMP12
SCHEMBL24372592 0.82 FFAR1 (0.50) FFAR1FDFT1HDAC2HDAC1MMP12
SCHEMBL8619956 0.82 ALDH1A1 (0.54) FFAR1FDFT1HDAC2HDAC1MMP12
SCHEMBL8622458 0.82 ALDH1A1 (0.54) FFAR1FDFT1HDAC2HDAC1MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11597784-B2 Enhanced yield, structural control, and transport properties of polynorbornenes for natural gas upgrading through Mizoroki-Heck cross-couplings SAUDI ARABIAN OIL COMPANY (SA) 2023-03-07 US disclosed
US-20210324118-A1 ENHANCED YIELD, STRUCTURAL CONTROL, AND TRANSPORT PROPERTIES OF POLYNORBORNENES FOR NATURAL GAS UPGRADING THROUGH MIZOROKI-HECK CROSS-COUPLINGS SAUDI ARABIAN OIL COMPANY (SA) 2021-10-21 US disclosed
WO-2021202343-A1 ENHANCED YIELD, STRUCTURAL CONTROL, AND TRANSPORT PROPERTIES OF POLYNORBORNENES FOR NATURAL GAS UPGRADING THROUGH MIZOROKI-HECK CROSS-COUPLINGS SAUDI ARABIAN OIL COMPANY (SA) 2021-10-07 WO disclosed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP disclosed
EP-1555267-B1 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES OTSUKA PHARMA CO LTD (JP) 2013-01-16 EP disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US disclosed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 US disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11597784-B2 Enhanced yield, structural control, and transport properties of polynorbornenes for natural gas upgrading through Mizoroki-Heck cross-couplings PNKP, GRK1, LNPK FFAR1 1522/4885FDFT1 1544/4885HDAC2 4585/4885
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 FFAR1 105/4885FDFT1 852/4885HDAC2 502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.