Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30869989 | 0.92 | HDAC2 (0.60) | HTR2AMAOBFFAR1TAAR1HDAC2 | |
| SCHEMBL5551465 | 0.89 | FFAR1 (0.60) | HTR2AMAOBFFAR1TAAR1MAOA | |
| SCHEMBL9069707 | 0.89 | HTR2A (0.75) | HTR2AMAOBHDAC2SIGMAR1MAOA | |
| SCHEMBL15347959 | 0.86 | HTR2A (0.71) | HTR2AMAOBFFAR1HDAC2SIGMAR1 | |
| SCHEMBL28353517 | 0.86 | HTR2A (0.64) | HTR2AMAOBTAAR1HDAC2SIGMAR1 | |
| Tannin Pyrogallol SCHEMBL29187612 | 0.86 | ALDH1A1 (0.56) | HTR2AMAOBFFAR1TAAR1MAOA | |
| SCHEMBL54347 | 0.86 | HTR2A (0.70) | HTR2AMAOBTAAR1HDAC2SIGMAR1 | |
| SCHEMBL24372592 | 0.83 | FFAR1 (0.50) | HTR2AMAOBFFAR1TAAR1HDAC2 | |
| SCHEMBL5540653 | 0.83 | FFAR1 (0.55) | FFAR1TAAR1HDAC2FDFT1MMP12 | |
| SCHEMBL8623391 | 0.83 | LTA4H (0.56) | FFAR1TAAR1HDAC2FDFT1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255243-B1 | AZOLE DERIVATIVES USEFUL FOR CONTROLLING PLANT DISEASES | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-05-29 | — | — | EP | claimed |
| EP-0255243-A1 | Azole derivatives useful for controlling plant diseases | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1988-02-03 | — | — | EP | claimed |