SCHEMBL5540869

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5542711	1.00	HDAC1 (0.51)	HDAC1HDAC8TAAR1HRH3SLC6A5
	SCHEMBL5538857	0.93	HDAC1 (0.50)	HDAC1HDAC8TAAR1HRH3SLC6A5
	SCHEMBL5535468	0.86	TAAR1 (0.50)	HDAC1HDAC8TAAR1MIFMAOB
	SCHEMBL5540228	0.82	HDAC1 (0.53)	HDAC1HDAC8TAAR1MIFCNR1
	SCHEMBL5537488	0.80	SLC6A5 (0.44)	HDAC1SLC6A5DAO
	SCHEMBL5540875	0.79	HDAC1 (0.53)	HDAC1HDAC8TAAR1HRH3SLC6A5
	SCHEMBL5542719	0.79	HDAC1 (0.53)	HDAC1HDAC8TAAR1HRH3SLC6A5
	SCHEMBL3245715	0.78	HDAC1 (0.51)	HDAC1HDAC8TAAR1PTPN2PTPN1
	SCHEMBL5250174	0.78	SIGMAR1 (0.62)	—
	SCHEMBL11104163	0.78	SIGMAR1 (0.62)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.