SCHEMBL5541704

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5537269	0.90	ADRB2 (0.52)	ADRB2TEAD1LIPEMMP13MMP12
	SCHEMBL5545720	0.86	ADRB2 (0.49)	ADRB2TEAD1LIPEMMP13MMP12
	SCHEMBL5537589	0.85	ADRB2 (0.48)	ADRB2TEAD1LIPEMMP13MMP12
	SCHEMBL5543304	0.84	ADRB2 (0.47)	ADRB2TEAD1LIPEMMP13MMP12
	SCHEMBL5548401	0.83	TP53 (0.56)	EPHX2HRH3CARM1PRMT6
	SCHEMBL5536138	0.83	TEAD1 (0.53)	ADRB2TEAD1LIPEMMP13MMP12
	SCHEMBL5543690	0.82	ADRB2 (0.54)	ADRB2TEAD1LIPEMMP13MMP12
	SCHEMBL10608877	0.80	HRH3 (0.64)	ADRB2HRH3
	SCHEMBL11938942	0.80	SLC6A5 (0.53)	ADRB2TEAD1LIPEMMP13MMP12
	SCHEMBL29090107	0.80	TEAD1 (0.59)	ADRB2TEAD1LIPEMMP13MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.