SCHEMBL5541922

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5545749	0.82	CA12 (0.47)	MAPK1ALDH1A1HTTL3MBTL1CA12
	SCHEMBL2096836	0.82	HTT (0.79)	MAPK1ALDH1A1HTTL3MBTL1AR
	SCHEMBL11208196	0.81	MAPK1 (0.58)	MAPK1ALDH1A1HTTL3MBTL1AR
	SCHEMBL19296417	0.79	ALDH1A1 (0.47)	MAPK1ALDH1A1HTTL3MBTL1AR
	SCHEMBL11120637	0.78	SMN1; SMN2 (0.58)	MAPK1ALDH1A1HTTL3MBTL1SMN1; SMN2
	SCHEMBL2095251	0.76	MAPK1 (0.47)	MAPK1ALDH1A1HTTL3MBTL1AR
	SCHEMBL17508212	0.76	ALDH1A1 (0.57)	MAPK1ALDH1A1HTTL3MBTL1AR
	SCHEMBL5535849	0.75	AR (0.41)	ALDH1A1L3MBTL1ARCYP1A2TSHR
	SCHEMBL2092523	0.74	TUBB4A (0.59)	MAPK1ALDH1A1HTTL3MBTL1AR
	SCHEMBL5534722	0.73	CA1 (0.48)	MAPK1ALDH1A1HTTL3MBTL1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.