Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | RARB | P10826 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | RARA | P10276 | 2/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | TACR2 | P21452 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5544425 | 1.00 | HSD17B10 (0.64) | HSD17B10TSHRRARBALDH1A1MEN1 | |
| SCHEMBL28518716 | 1.00 | HSD17B10 (0.64) | HSD17B10TSHRRARBALDH1A1MEN1 | |
| SCHEMBL17022435 | 1.00 | HSD17B10 (0.64) | HSD17B10TSHRRARBALDH1A1MEN1 | |
| SCHEMBL983507 | 1.00 | HSD17B10 (0.64) | HSD17B10TSHRRARBALDH1A1MEN1 | |
| SCHEMBL3090093 | 1.00 | HSD17B10 (0.64) | HSD17B10TSHRRARBALDH1A1MEN1 | |
| SCHEMBL981933 | 0.98 | HSD17B10 (0.61) | HSD17B10TSHRRARBALDH1A1MEN1 | |
| SCHEMBL6754529 | 0.92 | RARB (0.55) | HSD17B10TSHRRARBALDH1A1MEN1 | |
| SCHEMBL980959 | 0.92 | RARB (0.55) | HSD17B10TSHRRARBALDH1A1MEN1 | |
| SCHEMBL2967935 | 0.88 | PTGS2 (0.57) | HSD17B10TSHRALDH1A1ESR1ADRA2A | |
| SCHEMBL225807 | 0.88 | PTGS2 (0.57) | HSD17B10TSHRALDH1A1ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| EP-0813571-A1 | FLAME RETARDANT FOR STYRENE RESIN AND RESIN COMPOSITION COMPRISING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996027637-A1 | FLAME RETARDANT FOR STYRENE RESIN AND RESIN COMPOSITION COMPRISING THE SAME | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1996-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | HSD17B10 467/4885TSHR 319/4885RARB 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.