Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 6/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5535927 | 1.00 | LMNA (0.40) | LMNAKDM4EL3MBTL1PKMKMT2A | |
| SCHEMBL5535923 | 1.00 | LMNA (0.40) | LMNAKDM4EL3MBTL1PKMKMT2A | |
| SCHEMBL6010797 | 0.84 | ABCB1 (0.44) | LMNAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL5535042 | 0.84 | ABCB1 (0.44) | LMNAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL6010674 | 0.84 | ABCB1 (0.44) | LMNAL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL6010681 | 0.82 | PKM (0.35) | LMNAL3MBTL1PKMKMT2AALDH1A1 | |
| SCHEMBL6010806 | 0.82 | PKM (0.35) | LMNAL3MBTL1PKMKMT2AALDH1A1 | |
| SCHEMBL6010687 | 0.82 | PKM (0.35) | LMNAL3MBTL1PKMKMT2AALDH1A1 | |
| SCHEMBL5543095 | 0.80 | MAPT (0.47) | LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL5543102 | 0.80 | MAPT (0.47) | LMNAKMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |