Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL7472691 | 0.90 | KMT2A (0.39) | MAOAMAOBABCB1LTB4RLTB4R2 | |
| SCHEMBL9348186 | 0.80 | CYP2C9 (0.39) | ABCB1LTB4RLTB4R2KMT2AMEN1 | |
| SCHEMBL12236947 | 0.78 | ABCB1 (0.41) | MAOAMAOBABCB1KMT2AMEN1 | |
| SCHEMBL13062858 | 0.78 | ABCB1 (0.57) | MAOAMAOBABCB1KMT2AMEN1 | |
| SCHEMBL22519097 | 0.78 | ABCB1 (0.36) | MAOAMAOBABCB1LTB4RLTB4R2 | |
| SCHEMBL30997925 | 0.78 | ABCB1 (0.36) | MAOAMAOBABCB1LTB4RLTB4R2 | |
| SCHEMBL9345601 | 0.77 | CYP2C9 (0.38) | ABCB1LTB4RLTB4R2KMT2AMEN1 | |
| SCHEMBL5542835 | 0.77 | ABCB1 (0.41) | MAOAMAOBABCB1KMT2AMEN1 | |
| SCHEMBL13551756 | 0.77 | ABCB1 (0.41) | MAOAMAOBABCB1KMT2AMEN1 | |
| SCHEMBL13511910 | 0.77 | ABCB1 (0.38) | MAOAMAOBABCB1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112261-B1 | 2-ETHYL-2,3-DIHYDROBENZOFURAN-CARBOXYLIC ACID ESTER DERIVATIVE, PREPARATION METHOD AND USE FOR PREPARING EFAROXAN DERIVATIVES | PIERRE FABRE SANTE S A (FR) | 2002-04-10 | — | — | EP | claimed |
| EP-1112261-A1 | 2-ETHYL-2,3-DIHYDROBENZOFURAN-CARBOXYLIC ACID ESTER DERIVATIVE, PREPARATION METHOD AND USE FOR PREPARING EFAROXAN DERIVATIVES | PIERRE FABRE SANTE S.A. (FR) | 2001-07-04 | — | — | EP | claimed |
| WO-2000015624-A1 | 2-ETHYL-2,3-DIHYDROBENZOFURAN-CARBOXYLIC ACID ESTER DERIVATIVE, PREPARATION METHOD AND USE FOR PREPARING EFAROXAN DERIVATIVES | PIERRE FABRE SANTE, SOCIETE ANONYME (FR) | 2000-03-23 | — | — | WO | claimed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| EP-1112261-B1 | 2-ETHYL-2,3-DIHYDROBENZOFURAN-CARBOXYLIC ACID ESTER DERIVATIVE, PREPARATION METHOD AND USE FOR PREPARING EFAROXAN DERIVATIVES | PIERRE FABRE SANTE S A (FR) | 2002-04-10 | — | — | EP | disclosed |
| EP-1112261-A1 | 2-ETHYL-2,3-DIHYDROBENZOFURAN-CARBOXYLIC ACID ESTER DERIVATIVE, PREPARATION METHOD AND USE FOR PREPARING EFAROXAN DERIVATIVES | PIERRE FABRE SANTE S.A. (FR) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015624-A1 | 2-ETHYL-2,3-DIHYDROBENZOFURAN-CARBOXYLIC ACID ESTER DERIVATIVE, PREPARATION METHOD AND USE FOR PREPARING EFAROXAN DERIVATIVES | PIERRE FABRE SANTE, SOCIETE ANONYME (FR) | 2000-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | MAOA 2885/4885MAOB 2140/4885ABCB1 2408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.